Microsphere Localization Using PET/MRI or PET/CT in Patients Following Radioembolization

Pilot Study of Microsphere Localization Using PET/MRI or PET/CT in Patients Following Radioembolization

The successful localization of the y90 microspheres by PET/MR and/or PET/CT scans would be a useful tool in individualizing patient care after the radioembolization procedure. The information from a PET/MR or PET/CT scan would allow for early evaluation of the technical success of the procedure.

Inclusion Criteria:

• Participant must successfully complete the MRI screening form if receiving an MRI
• Participant must be scheduled to undergo radioembolization for any indication
• Participant must be ≥ 18 years of age
• Participant must be able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent document

Exclusion Criteria:

• Participant must not have any contraindications to MRI scanning
• Patient must not be pregnant or breastfeeding
• If agreeing to MRI contrast, participant must not have renal insufficiency (glomerular filtration rate (GFR < 30 mL/min/1.73 m2) measured within the past 60 days
• If agreeing to MRI contrast, participant must not be on dialysis
• If agreeing to MRI contrast, participant must not have had a prior allergic reaction to gadolinium-based contrast agents
• PET/MRI or PET/CT is not able to be scheduled within 72 hours of radioembolization