Clinical Study for the Impact of Bio-absorbable Felt (NEOVEIL®) With Fibrin Sealant on Removal of Drainage Tube After Minimally Invasive Gastrectomy for Gastric Cancer

Clinical Study for the Impact of Bio-absorbable Felt (NEOVEIL®) With Fibrin Sealant on Removal of Drainage Tube After Minimally Invasive Gastrectomy for Gastric Cancer: Multicenter Prospective Randomized Comparison Study

This study is to evaluate if Bio-absorbable Felt(NEOVEIL®) makes the amount of exudate reduce and shortens time until drain removal after minimally invasive surgery for early gastric cancer.

We investigate the effect on drainage amount of Bio-absorbable Felt(NEOVEIL®) after D1+b or D2 lymphadenectomy with distal gastrectomy for early gastric cancer.

This study is an randomised controlled trial undertaken in 7 centers in South Korea. Patients with stage I-II gastric cancer who is going to have curative distal gastrectomy with D1+b or D2 lymphadenectomy are randomly assigned to use bio-absorbable felt(NEOVEIL®) or not to use it. Block randomisation will be done by a central interactive computerised system, stratified by center.

Inclusion Criteria:

• histologic confirmed gastric adenocarcinoma
• Patients who underwent laparoscopic distal gastrectomy.
• preoperative clinical stage I diagnosed with esophagogastroduodenoscopy,endoscopic ultrasonography and computerized tomography.
• patients who underwent more than D1+b lymphadenectomy

Exclusion Criteria:

• Vulnerable participants (pregnant women, under 20 year old, and so on)
• liver or renal disease (Ex. liver cirrhosis, end stage renal disease)
• Transfusion is needed preoperatively or postoperatively due to bleeding
• Preoperative or intraoperative evaluation confirm ascites.
• Patients who use anticoagulant preoperatively or postoperatively