Early Hydration in Acute Myocardial Infarction | NCT01742130 | Trialant

Early Hydration in Acute Myocardial Infarction | NCT01742130 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Sodium bicarbonate	Experimental	Sodium Bicarbonate (154 mEq/L in dextrose and H2O) 3 mL/kg for 1 hour before contrast medium, followed by an infusion of 1 mL/kg/h for 12 hours after the procedure	Drug: sodium bicarbonate solution
Saline	Active Comparator	Sodium Saline 3 mL/kg for 1 hour before contrast medium, followed by an infusion of 1 mL/kg/h for 12 hours after the procedure	Drug: Isotonic saline

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Incidence of contrast-induced acute kidney injury	contrast-induced acute kidney injury is defined as an increase in serum creatinine >= 0.3 mg/dL over the baseline value within 2 days after the administration of the contrast medium	2 days

Intervention Browse Module