Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Median Klinik Berlin-Kladow | UNKNOWN |
| NeuroCure Clinical Research Center, Charite, Berlin | OTHER |
| Center for Stroke Research Berlin | OTHER |
| Free University of Berlin |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Healthy subjects will undergo cathodal stimulation of the right posterior parietal Cortex (PPC) and assessment of neglect-like symptoms in the encircling monitor system (EMS) as well as in a standard clinical test (Test Battery for Attention Performance, TAP, Zimmermann & Fimm, 1993). The aim of this study is to investigate whether cathodal stimulation leads to poorer test performance.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cathodal tDCS in young study participants | Experimental | Cathodal tDCS in young study participants |
|
| Cathodal tDCS in elderly study participants | Experimental | Cathodal tDCS in elderly study participants |
|
| Sham tDCS in young study participants | Sham Comparator | Sham tDCS in young study participants |
|
| Sham tDCS in elderly study participants | Sham Comparator | Sham tDCS in elderly study participants |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cathodal tDCS | Other | Cathodal tDCS applied over the right PPC |
|
| Measure | Description | Time Frame |
|---|---|---|
| Test performance of young study participants in the encircling monitor system with/without cathodal stimulation | Comparison of the young subjects' performance with vs. without transcranial direct current stimulation (tDCS) in the following computerised tests: Star Cancellation (number of omissions, latency & crossing index; based on Rabufetti, 2012), Landmark (reaction times, accuracy; based on Giglia et al., 2011), Visual Detection (reaction times, omissions; based on Sparing et al., 2009), Extinction (number of correct responses; based on Niedeggen & Hoffmann, 2011) |
| Measure | Description | Time Frame |
|---|---|---|
| Test performance of elderly study participants in the encircling monitor system with/without cathodal stimulation | Comparison of the performance with vs. without transcranial direct current stimulation (tDCS) in the following tests: Star Cancellation, Landmark, Visual Detection, Extinction (see above) | |
| Test performance of study participants in the Test Battery for Attention Performance (TAP) with/without cathodal stimulation |
Not provided
Inclusion Criteria:
Younger subjects
Elderly subjects
Exclusion Criteria:
- Exclusion criteria for both groups:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Andreas Meisel, MD | Charite - Universitätsmedizin Berlin (NeuroCure Clinical Research Center) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charité University Medicine | Berlin | 10117 | Germany |
Not provided
| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
Not provided
Not provided
| OTHER |
| Humboldt-Universität zu Berlin | OTHER |
Not provided
Not provided
Not provided
Not provided
| Sham tDCS | Other | Sham tDCS applied over the right PPC |
|
Comparison of reaction times and number of omissions in the left and right visual field in the TAP subtest "Neglect" with vs. without tDCS. |
| Comparison of visual search patterns between neglect patients and healthy subjects with cathodal stimulation | Comparison of visual search direction, structuredness (crossing index), and omissions in the Star Cancellation Test |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |