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The purpose of this study is to compare two regimens of low volume (2L) polyethylene glycol(PEG)plus ascorbic acid versus standard volume (4L) PEG alone for bowel preparation in out-patients
Inadequate bowel preparation may lead to a longer colonoscopy, and to an inability to identify lesions. PEG can provide a rapid orthograde peroral approach to colonic lavage without producing significant fluid or electrolyte changes. Thus PEG is now commonly used for bowel preparation. However, large amounts and unsatisfactory taste of PEG solution are generally poorly tolerated. a new low volume PEG-based bowel cleansing agents became available at foreign countries. Although several studies reported the efficacy and improved compliance of these low volume PEG plus ascorbic acid solution for colonoscopy, but result in Korean patients was not-recognized.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PEG + ascorbic acid | Those who taken PEG 2L + ascorbic acid |
| |
| PEG 4L | Those who taken PEG 4L alone |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| polyethylene glycol, ascorbic acid | Drug | comparison of different solutions for bowel preparation |
|
| Measure | Description | Time Frame |
|---|---|---|
| The efficacy of bowel preparation | three segmental preparation scoring (0~4, Rt., mid, Lt.colon) total preparation grade:A,B,C,D (A or B was defined successful bowel cleansing) Influence of the intake of additional fluid in PEG+ascorbic acid | one day (after colonoscopy) |
| Measure | Description | Time Frame |
|---|---|---|
| Patient's compliance and acceptability | satisfaction (Visual Analogue Scale) amount of ingestion, frequency and amount of vomiting, tolerability, complication, taste | one day (after injestion of preparation solution) |
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Inclusion Criteria:
Exclusion Criteria:
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Out-patients for colonoscopy in university hospital
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| Name | Affiliation | Role |
|---|---|---|
| Dong Il Park, professor | Kangbuk Samsung Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kangbuk Samsung Hospital | Seoul | Seoul | 110-746 | South Korea |
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| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D011092 | Polyethylene Glycols |
| D001205 | Ascorbic Acid |
| ID | Term |
|---|---|
| D005026 | Ethylene Glycols |
| D006018 | Glycols |
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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| D011108 |
| Polymers |
| D046911 | Macromolecular Substances |
| D001697 | Biomedical and Dental Materials |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
| D013400 | Sugar Acids |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D006880 | Hydroxy Acids |
| D002241 | Carbohydrates |