Examine the effects and safety of functional oil (olive oil with omega 3 fatty acids from fish oil) on different inflammatory markers in obese subjects with dietary intervention for weight lost.

Inclusion Criteria:

• Men and women from 30 to 75 years old.
• Body mass index (BMI) ≥ 30 kg/m2
• Signed informed consent.

Exclusion Criteria:

• Individuals with special diet due to disease as celiac disease, chronic renal failure, etc.
• Individuals with Diabetes Mellitus insulin dependent.
• Individuals with disorders associated with eating behaviour.
• Individuals with mental disease or low cognitive function.
• Individuals with consumption of drugs to weight lost.
• Individuals treated with drugs whose direct effect is on lipid profile (statins, fibrates, diuretics, corticosteroids or oral anti-inflammatory).
• Individuals with diseases that could be involucrate in weight lost (not controlled hypothyroidism, serious psychiatric illness, etc.)
• Pregnant women or lactating.
• Individuals with recurrent infections.
• Individuals with regular consumption of anti-inflammatory or glucocorticoids.
• Individuals with consumption of oil fish supplements (except if they gave up its consumption 1 month before).
• Individuals with fish allergy.
• Individuals with consumption of more than two fatty fish servers twice a week.
• Individuals with physical problems complying with the recommendations of physical activity and diet indicated.