Safety and Efficacy of Low-Fluence PRP for PDR

Safety and Efficacy of Single-session, Low-fluence Panretinal Photocoagulation (PRP) for Proliferative Diabetic Retinopathy (PDR)

To determine the safety and efficacy of a single session of low-fluence panretinal photocoagulation when compared to full-fluence PRP. Hypothesis: a single-session of low-fluence PRP will be safe regarding the progression of macular edema and the presence of adverse events, and will efficiently induce regression of neovascularization.

Inclusion Criteria:

• Type 1 or type 2 diabetics
• Proliferative diabetic retinopathy

Exclusion Criteria:

• Previous treatment with PRP
• Media opacities
• Previous treatment for macular edema (LASER or intravitreal injections)
• Recent (less than 6 months) ophthalmic surgery
• Only eyes
• Intra-retinal or sub-retinal fluid with foveal involvement
• Chronic renal failure
• History of liver or pancreatic transplant