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We are doing this study to find out how well cognitive behavioural therapy for social phobia works in people with bipolar disorder, who also have social phobia.
Social phobia is a very prevalent anxiety disorder in people with bipolar disorder and is associated with adverse outcomes. Yet, social phobia is treatable by cognitive behavioural therapy or antidepressant medication. As antidepressants are often contra-indicated in people with bipolar disorder, cognitive behavioural therapy is the likely first choice treatment for social phobia in this population. However, people with bipolar disorder were excluded from previous clinical trials on treatment of social phobia. Our aim is to evaluate the acceptability and to provide a rough estimate of efficacy of cognitive behavioural therapy protocol for social phobia in people with bipolar disorder in a systematic case series. We will also prepare pilot data for evaluating the impact of treatment of comorbid social phobia on the long-term course of bipolar disorder.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cognitive behavioural therapy | Experimental | Cognitive behavioural therapy for social phobia in people with bipolar disorder |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cognitive behavioural therapy (CBT) | Behavioral | The CBT intervention will follow the model of social phobia by Clark & Wells (Clark & Wells, 1995; Clark, 2005). The main elements of CBT for social phobia include reducing self-focus, dropping safety behaviours, and testing negative cognitions. |
| Measure | Description | Time Frame |
|---|---|---|
| Acceptability of cognitive behavioural therapy for comorbid social phobia in bipolar disorder | Acceptability of cognitive behavioural therapy for comorbid social phobia in bipolar disorder will be assessed as proportion of offered sessions attended | up to end of treatment (20 weeks) |
| Change on the Social Phobia Inventory (SPIN) | Baseline and end of treatment (20 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Change on the Liebowitz Social Anxiety Scale Scale Self-Report; Social Phobia Scale & Social Interaction Anxiety Scale; Social Phobia and Anxiety Inventory | Baseline and end of treatment (20 weeks) | |
| Presence/absence of the social phobia diagnosis | Presence/absence of the social phobia diagnosis as established by Structured Clinical Interview for DSM Disorders |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Barbara Pavlova, PhD DClinPsy | Capital Health, Canada | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Queen Elizabeth II Health Sciences Centre | Halifax | Nova Scotia | B3H 2E2 | Canada |
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| ID | Term |
|---|---|
| D000072861 | Phobia, Social |
| D001714 | Bipolar Disorder |
| ID | Term |
|---|---|
| D010698 | Phobic Disorders |
| D001008 | Anxiety Disorders |
| D001523 | Mental Disorders |
| D000068105 | Bipolar and Related Disorders |
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| ID | Term |
|---|---|
| D015928 | Cognitive Behavioral Therapy |
| ID | Term |
|---|---|
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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|
| Baseline and end of treatment (20 weeks) |
| Depression symptom change | Depression symptom change as established by the Montgomery-Åsberg Depression Rating Scale and Beck Depression Inventory II | Baseline and end of treatment (20 weeks) |
| Mania symptom change | Change in symptoms of mania as established by the Young Mania Rating Scale | Baseline and end of treatment (20 weeks) |
| D019964 |
| Mood Disorders |