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The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Prunus Mume Extract on Improvement of Constipation. The investigators measured Improvement of Constipation parameters , including Colonic Transit Time, number of bowel movement, defecation time, stool type, color and stool amounts per defecation, and monitored their blood pressure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Prunus Mume Extract | Experimental |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prunus Mume Extract | Dietary Supplement | Prunus Mume Extract (3.94g/day) |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Colonic Transit Time | Colonic Transit Time was measured in study visit 1(0 week) and visit 3(8 week). | 8 weeks |
| Changes in number of bowel movement | Number of bowel movement was measured in study visit 1(0 week) and visit 3(8 week). | 8 weeks |
| Changes in defecation time | Defecation time was measured in study visit 1(0 week) and visit 3(8 week). | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in stool type | Stool type was measured in study visit 1(0 week) and visit 3(8 week). | 8 weeks |
| Changes in stool color | Stool color was measured in study visit 1(0 week) and visit 3(8 week). |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Trial Center for Functional Foods; Chonbuk National University Hospital | Recruiting | Jeonju | Jeollabuk-do | 560-822 | South Korea |
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| ID | Term |
|---|---|
| D003248 | Constipation |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Placebo |
| Dietary Supplement |
Placebo (3.94g/day) |
|
| 8 weeks |
| Changes in stool amounts per defecation | Stool amounts per defecation was measured in study visit 1(0 week) and visit 3(8 week). | 8 weeks |