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This cross-sectional, non-interventional, and observational study will assess the lipid profile of patients who have been taking lipid-modifying drugs (i.e., proportion of patients achieving treatment to goal according to national and international lipid management guidelines) during a single visit to their physicians on an outpatient basis in 6 representative geo-economic regions in China: Northeast, North, East, South, Southwest, and Northwest; and within each region, in three tiers of hospitals: tier 3 (primary or teaching hospitals), tier 2 (secondary or city level hospitals), and tier 1 (community hospitals/health centers). The investigators will primarily be cardiologists, endocrinologists, neurologists, gerontologists, internists, or other physicians who are representative of the general population of physicians managing patients with dyslipidemia and/or at high risk for cardiovascular events likely to be treated with lipid-modifying drugs. Demographic data, cardiovascular risk factors, a history of cardiovascular disease and cardiovascular treatments will be documented in a single visit through patient clinical examination and chart review.
DYSIS-China is part of a string of epidemiological studies that share the same master protocol, which has been conducted in different countries mainly in Europe and Canada. The analysis of the pooled studies including overall data and cross-country comparisons is the subject of a distinct protocol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| regions,hospitals,age, gender, risk levels, comorbidity, |
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| Measure | Description | Time Frame |
|---|---|---|
| the prevalence and types of persistent lipid abnormalities in patients aged > 45 years treated with a lipid-modifying drug | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| assess patient characteristics, including CV risk levels, in the subsets of patients with persistent lipid abnormalities | 6months |
| Measure | Description | Time Frame |
|---|---|---|
| explore a potential relationship between the persistence of lipid abnormalities and the local known (historical) prevalence of CV morbidity/mortality | 6months |
Inclusion Criteria:
Patient is an outpatient > 45 years of age
Patient is currently* treated with a statin
Patient has a documented fasting lipid profile (> 1 lipid parameter within the last 12 months) performed while on lipid-modifying therapy for at least 3 months
Patient agrees to participate in the study by giving informed consent.
Exclusion Criteria:
1. Patient is currently participating in a clinical trial.
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Patient is an outpatient > 45 years of age
Patient is currently* treated with a statin
Patient has a documented fasting lipid profile (> 1 lipid parameter within the last 12 months) performed while on lipid-modifying therapy for at least 3 months
Patient agrees to participate in the study by giving informed consent.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hu da yi, Dr. | Contact | 8601088324876 | dayi.hu@medmail.com.cn |
| Name | Affiliation | Role |
|---|---|---|
| Hu da yi, Dr. | Chinese Society of Cardiology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peiking University People' Hospital | Recruiting | Beijing | Beijing Municipality | 100044 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34540919 | Derived | Chen Y, Yin C, Li Q, Yu L, Zhu L, Hu D, Sun Y. Misuse of Aspirin and Associated Factors for the Primary Prevention of Cardiovascular Disease. Front Cardiovasc Med. 2021 Sep 3;8:720113. doi: 10.3389/fcvm.2021.720113. eCollection 2021. | |
| 30696435 | Derived | Yan X, Li Y, Dong Y, Wu Y, Li J, Bian R, Hu D. Blood pressure and low-density lipoprotein cholesterol control status in Chinese hypertensive dyslipidemia patients during lipid-lowering therapy. Lipids Health Dis. 2019 Jan 29;18(1):32. doi: 10.1186/s12944-019-0974-y. |
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