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This study will evaluate the absorption of lutein when consumed in different oil blends.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control capsule | Active Comparator | 2 capsules |
|
| Experimental capsule | Experimental | 2 capsules |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Study product containing lutein | Other | delivered in capsule form |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma lutein | adjusted area under the curve at specified postprandial timepoint | baseline and 336 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma carotenoids | mean concentrations at specified postprandial timepoints | 2, 4, 6, 8, 12, 24, 48, and 336 hours |
| Plasma lipid concentrations | averaged concentrations at specified postprandial timepoints |
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Inclusion Criteria:
Subjects will be eligible for the study if they meet all of the following inclusion criteria:
BMI ≥ 18 and ≤ 25 kg/m2
Between 18 and 45 years of age, inclusive
Male or a non-pregnant, non-lactating female, nulliparous or at least 6 weeks postpartum prior to screening visit. A urine pregnancy test is required for all female subjects unless she is not of childbearing potential. If female is of childbearing potential, is practicing one of the following methods of birth control (and will continue through the duration of the study):
If on a chronic medication, subject has been on constant dosage for at least two months prior to screening visit
Exclusion Criteria:
Subjects will be excluded from the study if they meet any of the following criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jennifer Williams | Abbott Nutrition | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Biofortis Clinical Research | Addison | Illinois | 60101 | United States |
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| Study product containing lutein |
| Other |
delivered in capsule form |
|
| baseline and 48 hours |