Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients

Helicobacter Pylori Infection and Chronic Immune Thrombocytopenic Purpura in Children and Adolescents - A Randomized Controlled Trial

The purpose of this study is to determine whether eradication of Helicobacter pylori infection is effective in the improvement of platelet counts in children and adolescents with chronic ITP.

Helicobacter pylori infection has been associated with Immune Thrombocytopenic Purpura (ITP), and there is scientific evidence for the investigation and treatment of this bacterium for adult patients with ITP. However, in children this causal association is not clear, with few published studies.

Inclusion Criteria:

• clinical diagnosis of chronic immune thrombocytopenic purpura
• children and adolescents up to 20 years

Exclusion Criteria:

• known hypersensitivity to any of the drugs
• recent treatment for H. pylori eradication