The purpose of this study is to evaluate the safety and efficacy of a soy based dietary supplement (phytoSERM) for hot flashes and age associated memory loss.

Inclusion Criteria:

• post-menopausal women
• ages 45 - 60 (inclusive)
• must have a vasomotor symptom (e.g., hot flash) and a memory complaint

Exclusion Criteria:

• history of clinically significant stroke
• current evidence or history in past 2 years of epilepsy, seizure, focal brain lesion, head injury with loss of consciousness or any major psychiatric disorder including psychosis, major depression, bipolar disorder, alcohol or substance abuse
• Known allergy to soy derived products; hypersensitivity to estrogens or progestins