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| Name | Class |
|---|---|
| Medical Corps, Israel Defense Force | OTHER |
| Walter Reed Army Institute of Research (WRAIR) | FED |
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Military deployment to combat zones involves exposure to trauma at a higher than average rate and therefore presents a unique opportunity to study predisposing factors to posttraumatic stress reactions and test strategies designed to prevent and ameliorate posttraumatic symptoms. Decades of scientific research on the origins of resilience and vulnerability to combat-related posttraumatic stress symptoms revealed various predisposing and protective factors. All these factors however, offer limited opportunity for systematic pre-deployment prevention efforts. Considering the magnitude of psychological adjustment difficulties encountered by combat personnel in deployment and the limited access to existing evidence-based therapies for PTSD, the development and testing of a novel evidence-based and theory-driven prevention protocol for these problems is of considerable significance. The current study translates cognitive-neuroscience knowledge and attention bias modification research into a novel computerized training tool that could be easily delivered to soldiers during different stages of the deployment cycle. If proved efficacious in reducing risk for posttraumatic symptoms ABMT could be integrated into the Army's resilience training program. Thus, we propose a longitudinal double-blind randomized controlled study of ABMT in soldiers. We will assess attention bias and symptoms before deployment, will randomly assign soldiers to either 8 ABMT sessions, 4 ABMT sessions, 8 Placebo training sessions, or no training. Following 6 months of deployment to combat zone symptoms will be assessed again.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active ABMT8 | Active Comparator | Active ABMT8 8 active ABMT sessions (10 min. each, over 7-8 weeks) designed to promote adaptive threat attendance |
|
| Active ABMT4 | Active Comparator | Active ABMT4 4 active ABMT sessions (10 min. each, over 7-8 weeks) designed to promote adaptive threat attendance |
|
| Control | No Intervention | Control: will not receive any intervention | |
| Placebo | Placebo Comparator | Placebo: will receive 4 training sessions(10 min. each, over 7-8 weeks) using the same task and stimuli as in the active arms, but not designed to change attention patterns |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Active ABMT8 | Behavioral | Active ABMT8 8 active ABMT sessions (10 min. each, over 7-8 weeks) designed to promote adaptive threat attendance |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in PTSD symptoms(PCL) | 1. pre-treatment 2.after first deployment 3.10 days after combat 4. 4 months after combat | Pre-treatment(baseline), after first deployment, 10 days after combat, 4 months after combat |
| Probable PTSD diagnosis(CAPS) | Four months after combat | Four months after combat |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Depression(PHQ-9)) and Anxiety(STAI) | 1. Pre-treatment(baseline) 2.after first deployment 3.10 days after combat 4. 4 months after combat | Pre-treatment(baseline), after first deployment, 10 days after combat, 4 months after combat |
| Measure | Description | Time Frame |
|---|---|---|
| Attention Bias Scores | Attention bias scores measured in milliseconds using the dot-probe task | Pre-traetment baseline and in deployment |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yair Bar-Haim, PhD | Tel Aviv University | Principal Investigator |
| Eyal Fruchter | Mental Health Department IDF | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IDF Military camps | Beersheba | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20456540 | Background | Bar-Haim Y. Research review: Attention bias modification (ABM): a novel treatment for anxiety disorders. J Child Psychol Psychiatry. 2010 Aug;51(8):859-70. doi: 10.1111/j.1469-7610.2010.02251.x. Epub 2010 May 6. | |
| 20395400 | Background | Bar-Haim Y, Holoshitz Y, Eldar S, Frenkel TI, Muller D, Charney DS, Pine DS, Fox NA, Wald I. Life-threatening danger and suppression of attention bias to threat. Am J Psychiatry. 2010 Jun;167(6):694-8. doi: 10.1176/appi.ajp.2009.09070956. Epub 2010 Apr 15. |
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| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| D003863 | Depression |
| D001008 | Anxiety Disorders |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
| D001526 | Behavioral Symptoms |
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| Active ABMT4 | Behavioral | Active ABMT4 4 active ABMT sessions (10 min. each, over 7-8 weeks) designed to promote adaptive threat attendance |
|
| Placebo | Behavioral | Placebo: will receive 4 training sessions(10 min. each, over 7-8 weeks) using the same task and stimuli as in the active arms, but not designed to change attention patterns |
|
| 27377418 | Derived | Wald I, Fruchter E, Ginat K, Stolin E, Dagan D, Bliese PD, Quartana PJ, Sipos ML, Pine DS, Bar-Haim Y. Selective prevention of combat-related post-traumatic stress disorder using attention bias modification training: a randomized controlled trial. Psychol Med. 2016 Sep;46(12):2627-36. doi: 10.1017/S0033291716000945. Epub 2016 Jul 5. |
| D001519 | Behavior |