Anti-Mullerian Hormone Levels Before and After an Open Myomectomy

Anti-Mullerian Hormone Levels Variations Following an Open Myomectomy

Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. It is well known that ovarian surgery for endometriosis lowers Anti-Mullerian hormone, but little is known for other surgeries. We seek to investigate the hormone variations before and after an open myomectomy.

Hypothesis: Anti-Mullerian hormone levels drop following surgery but return to normal levels in a few months

Inclusion Criteria:

• 18 to 42 years old
• Requiring open myomectomy for any indication

Exclusion Criteria:

• Incapable of informed consent
• Use of hormonal contraception or Gonadotropin-releasing hormone agonists in the past 3 months
• Woman over 42 years old
• Post-menopause women
• Positive B-human chorionic gonadotropin the day of surgery
• Ovarian surgery (at the same time)
• Pre-operative AMH below 0.3 ng/mL