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| ID | Type | Description | Link |
|---|---|---|---|
| IDX-03YF |
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All subjects in this study have previously been in an Idenix HCV study and received study drug for 3 consecutive days. Subjects who had received placebo in a previous Idenix study will not be enrolled in this study.
In this study, researchers will try to find answers to these questions:
The data obtained from this study will be used to further understand the long-term efficacy of Idenix DAAs used to treat HCV infection and to further understand HCV resistance to Idenix DAAs.
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| Measure | Description | Time Frame |
|---|---|---|
| Durability of Sustained viral response [SVR] | To evaluate the durability of sustained virological response (SVR). Plasma HCV RNA levels will be monitored over time. | every 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Kinetics of resistant variants | To describe the kinetics of resistant variants to Idenix direct acting antivirals (DAAs) by HCV RNA sequencing. The presence of each identified resistant variant in the viral population will be descriptively evaluated until the viral population consists entirely of wild-type virus or over a period of 3 years, whichever comes first. | every 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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The population will include subjects who participated in studies of Idenix anti-HCV DAAs.
| ID | Term |
|---|---|
| D006526 | Hepatitis C |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D006525 | Hepatitis, Viral, Human |
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Human plasma
| D014777 |
| Virus Diseases |
| D018178 | Flaviviridae Infections |
| D012327 | RNA Virus Infections |
| D006505 | Hepatitis |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |