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| Name | Class |
|---|---|
| Prosperity Organic Foods | UNKNOWN |
| USDA Beltsville Human Nutrition Research Center | FED |
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The purpose of this study is to test the effects of a cooking oil blend of dietary fats rich in medium chain triglycerides on energy expenditure and food intake in overweight and obese children.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Melt (test oil) | Experimental | Participants will consume a muffin containing 20 g of dietary fat provided by the test oil and their energy expenditure will be measure post-prandially for 6 hours. At the end of the measurement period, participants will consume a cookie containing 10 g of fat provided by the test oil and their food intake at an ad libitum meal will be measured 1 hour later. |
|
| Corn oil (control) | Active Comparator | Participants will consume a muffin containing 20 g of dietary fat provided by the control oil and their energy expenditure will be measure post-prandially for 6 hours. At the end of the measurement period, participants will consume a cookie containing 10 g of fat provided by the control oil and their food intake at an ad libitum meal will be measured 1 hour later. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Melt (test oil) | Dietary Supplement |
| ||
| Corn oil (control) |
| Measure | Description | Time Frame |
|---|---|---|
| Thermic effect of food | Measurement of thermic effect of food over 6 hours after a meal rich in test oil and control oil. The thermic effect of food is the difference between post-prandial energy expenditure and basal energy expenditure. We will assess the difference in thermic effect of food over a 6-hour period between the test oil and the control oil. | 6 h |
| Respiratory quotient/fat oxidation | Measurement of substrate oxidation by indirect calorimetry over 6 hours after consumption of the test oil and control oil. We will specifically calculate carbohydrate and fat oxidation rates over the 6-hour period post-prandially and compare rates of oxidation of these two substrates between the test oil and the control oil. | 6 h |
| Food intake | Measurement of food intake at a single meal served 1 hour after a pre-load containing 8-10 g of the test oil and the control oil | single meal |
| Measure | Description | Time Frame |
|---|---|---|
| Glucose | Measurement of glucose over 6 hours after consumption of the test oil and control oil | 6 h |
| Feelings of appetite and satiety | Measurement of feelings of appetite and satiety by visual analog scales over 6 hours after consumption of the test oil and control oil |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marie-Pierre St-Onge, Ph.D | St. Luke's-Roosevelt Hospital Center | Principal Investigator |
| Cygnia Rapp | Prosperity Organic Foods | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St. Luke's/Roosevelt Hospital | New York | New York | 10025 | United States |
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| ID | Term |
|---|---|
| D063766 | Pediatric Obesity |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D005615 | Freezing |
| D003314 | Corn Oil |
| ID | Term |
|---|---|
| D044367 | Phase Transition |
| D055585 | Physical Phenomena |
| D003080 | Cold Temperature |
| D013696 | Temperature |
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|
| 6 h |
| Insulin | Measurement of insulin over 6 hours after consumption of the test oil and control oil | 6 hours |
| Leptin | Measurement of leptin over 6 hours after consumption of the test oil and control oil | 6 hours |
| Ghrelin | Measurement of ghrelin over 6 hours after consumption of the test oil and control oil | 6 hours |
| Peptide YY | Measurement of peptide YY over 6 hours after consumption of the test oil and control oil | 6 hours |
| Glucagon like peptide 1 | Measurement of glucagon like peptide 1 over 6 hours after consumption of the test oil and control oil | 6 hours |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013816 |
| Thermodynamics |
| D055598 | Chemical Phenomena |
| D004042 | Dietary Fats, Unsaturated |
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
| D005224 | Fats, Unsaturated |
| D010938 | Plant Oils |
| D009821 | Oils |
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |