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| ID | Type | Description | Link |
|---|---|---|---|
| NIH 1K126K63691 | Other Identifier | NIH |
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Our goal is to investigate how hormones that control blood sugar, hunger, and stomach emptying change with puberty and being overweight. These substances change with a meal.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Healthy lean children before puberty | ||
| Group B | Otherwise healthy overweight children before puberty | ||
| Group C | Healthy lean adolescents in mid to late puberty | ||
| Group D | Otherwise healthy overweight adolescents in mid to late puberty |
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| Measure | Description | Time Frame |
|---|---|---|
| Overweight and Lean Children Sugar Metabolism Before and During Puberty | Too much weight gain can cause changes in the substances that control blood sugar and hunger in the body. Scientists need to compare these substances in lean and overweight children before and during puberty. These substances can be measured before and after a meal in the blood and in the urine. The way your stomach moves food can change your sugar levels. We want to understand how diabetes develops by studying these things. This can help find better ways to prevent and treat diabetes. | 4 hours |
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Inclusion Criteria:
All groups:
Healthy lean and otherwise healthy overweight children and adolescents between the ages of 8 and 17.
Exclusion Criteria:
Same for all groups
The subjects will be excluded if they have:
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Prepubertal and pubertal subjects.
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| Name | Affiliation | Role |
|---|---|---|
| Luisa M. Rodriguez, MD | Baylor College of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Baylor College of Medicine | Houston | Texas | 77030 | United States |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D013851 | Thinness |
| D009765 | Obesity |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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plasma
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |