R2C2 study has shown that abdominal obesity is associated with a cardiac and vascular remodelling in healthy volunteers. This remodelling is correlated with renin-angiotensin aldosterone system (RAAS) activation and/or systemic fibrosis. R2C2 II study is designed to confirm the hypothesis that RAAS is associated with an early remodelling and implicated in the transition to cardiac failure in abdominal obesity.

Follow up of abdominal obesity patients from the R2C2 cohort study.

Inclusion Criteria:

• Being a former member of R2C2 study, abdominal obese group.
• Having signed the informed consent (refusing to participate to the genetic study is not an exclusion criteria).
• being affiliated to health insurance scheme.

Inclusion Criteria of R2C2 study:

• Men and women aged between 40 and 65 year's old
• Caucasian
• Born or living in France for at least 10 years
• Presenting an abdominal obesity defined by a waist circumference >94 cm in men and ≥ 80 cm in women, associated or not with untreated hypertension or hypertension treated for less than one year
• Having signed the informed consent

Exclusion Criteria:

• Subjects unable to understand the information letter
• Subjects under supervision or guardianship
• pregnant or lactating woman
• A contraindication to perform MRI is not an exclusion criteria.