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| Name | Class |
|---|---|
| Laboratoires URGO | INDUSTRY |
| University of Wolverhampton | OTHER |
| University of Birmingham | OTHER |
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How effective is sugar in reducing the debriding of sloughy, necrotic or infected exudating wounds compared with standard treatment?
Patients for whom all the following apply:
Have an exudating wound sizes 5cm2 and 40cm2 A minimum of 25% slough, infected and necrotic tissue No dry necrotic eschar present Ankle Brachial Pressure Index of greater than 0.6 Are over 18 years Independently and willingly consent
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chronic & Acute infected wounds | Experimental | Wound will be cleaned with normal saline or tap water and Granulated sugar will be applied directly to the wound and covered with an absorbent pad and held in place with a bandage and tape. |
|
| Chronic and Acute infected wounds | Active Comparator | Wound will be cleaned with normal saline or tap water and an appropriate debridement dressing (Aquacel or Sorbsan) is applied to the wound and secured with a bandage and surgical tape. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Granulated Sugar | Other | 30 grams of granulated sugar is used to cover the wound area and this is held in place using a dry dressing pad , bandage and tape. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Time to debridement of wound | wounds will be photographed at entry into the study there after weekly till end of study at 4 weeks | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Reduction in wound surface area | Wound measurements will be taken at entry into the study then weekly until end of 4 weeks | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life | Participants will be given a QOL questionnaire to complete before commencing the treatment and at the end of the 4 weeks | 4 weeks |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Moses Murandu, PhD student | Contact | 07743025072 | mosesmurandu@wlv.ac.uk | |
| Malcolm Simms, MBBSFRCS | Contact | 07768147025 | malcolm.simms@uhb.nhs.uk |
| Name | Affiliation | Role |
|---|---|---|
| Malcolm Simms, MBBSFRCS | University Hospital Birmingham NHS Fondation Trust | Principal Investigator |
| Moses Murandu, PhD student | University of Wolverhampton | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Birmingham NHS Foundation Trust | Recruiting | Birmingham | West Midlands | B15 2TH | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21647066 | Background | Murandu M, Webber MA, Simms MH, Dealey C. Use of granulated sugar therapy in the management of sloughy or necrotic wounds: a pilot study. J Wound Care. 2011 May;20(5):206, 208, 210 passim. doi: 10.12968/jowc.2011.20.5.206. |
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| ID | Term |
|---|---|
| D014946 | Wound Infection |
| ID | Term |
|---|---|
| D007239 | Infections |
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| ID | Term |
|---|---|
| D013395 | Sucrose |
| D002266 | Carboxymethylcellulose Sodium |
| C078112 | sorbsan |
| ID | Term |
|---|---|
| D004187 | Disaccharides |
| D009844 | Oligosaccharides |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
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|
| Debridement Dressing | Other | 1 Aquacel or Sorbsan dressing will be put over the wound, and held in place with a dry dressing pad, bandage and tape. |
|
|
| D000073893 |
| Sugars |
| D008747 | Methylcellulose |
| D002482 | Cellulose |
| D005936 | Glucans |