Preoperative Versus Postoperative Start With Thromboprophylaxis in THA (Total Hip Arthroplasty)

A Prospective Randomized, Double Blind Study to Evaluate Safety and Effect With Pre Versus Postoperative Start of Thromboprophylaxis With Dalteparin

The purpose of this study is to determine if there are differences in clinical events, i.e bleeding with associated morbidity, if thromboprophylaxis with LMWH (Low Molecular Weight Heparin) is initiated before or after surgery.

Inclusion Criteria:

-patients 50 years or older undergoing cemented total hip arthroplasty for primary osteoarthritis

Exclusion Criteria:

• allergy to Low-Molecular-Weight -Heparin
• bleeding disorders
• renal failure
• hepatic disease
• active treatment for malignancy
• history of deep venous thrombosis or pulmonary embolism
• major operations,trauma,stroke or cardiac infarction the last 3 months before surgery.