Oral Administration of Four Lactobacillus Species Preparation to Improve the Quality of the Neovaginal Flora in Male to Female Transsexual Patients

The aim of this study is the improvement of the penile linked neovaginal flora in male-to-female transsexuals after application of oral probiotics.

Inclusion Criteria:

Participants underwent the sex reassignment surgery (SRS) with the technique of the inverted penile skin flap longer than 1 year.

All transsexual women treated according to the Standards of Care of the World Professional Association of Transgender Health (WPATH).

Exclusion Criteria:

• clinical signs of vaginal or urinary tract infection,
• abnormal neovaginal discharge,
• neoplasia,
• bleeding,
• diarrhoea,
• constipation,
• rectal pathologies including hemorrhoids,
• antibiotic therapy in the previous 4 weeks