Serum Omentin-1 and Carotid Atherosclerosis In Non-Diabet... | NCT01701830

Studies
Serum Omentin-1 and Carotid Atherosclerosis In Non-Diabetic Chronic Kidney Disease

NCT01701830

Sponsor

Kocaeli Derince Education and Research Hospital

Status

Unknown status

Last Update Posted

Oct 5, 2012Estimated

Enrollment

85Estimated

Phase

Not provided

Conditions

Non-diabetic Chronic Kidney Disease
Atherosclerosis

Interventions

Not provided

Countries

Turkey (Türkiye)

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Oct 2012

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 2012

Primary Completion Date

Not provided

Completion Date

May 2013Estimated

First Submitted Date

Oct 3, 2012

First Submission Date that Met QC Criteria

Oct 4, 2012

First Posted Date

Oct 5, 2012Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Oct 4, 2012

Last Update Posted Date

Oct 5, 2012Estimated

Description Module

Brief Summary

The aim of the study is to evaluate whether a low level of serum omentin-1 is associated with carotid atherosclerosis and mediated by inflammation.

Detailed Description

Atherosclerotic cardiovascular disease is markedly increased in chronic kidney disease. There are a lot of risk factor, along with conventional risk factors. Serum onemtin-1 is a adipokine and suggested as a new marker for vascular disease.It has some anti-atherogenic properties. Studies investigating serum omentin-1 level have usually conducted in patients with diabetes mellitus.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

85Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Case Group		Patients with chronic kidney disease of stage 3-4.
Control group		30 healthy subject

Interventions

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

between ages of 18 - 65 years old chronic kidney disease of stage 3-4

Exclusion Criteria:

Chronic kidney disease of stage 5
The history of ischemic cardiovascular disease (myocardial infarction, unstable angina, stroke, peripheral artery disease, or cardiovascular revascularization)
Severe heart failure
Stage 2 hypertension
Diabetes mellitus
Corticosteroid therapy
Severe hepatic disease
Smoking
Inflammatory disease
Acute infectious disease
Malignancy

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

75 Years

Standard Ages

AdultOlder Adult

Study Population

Department of Nephrology, Check-up clinic

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Erkan SENGUL, MD	Kocaeli Derince Education and Training Hospital	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Department of Nephrology, Check-up Clinic,Kocaeli Derince Education and Traning Hospital	Recruiting	İzmit	Kocaeli	41100	Turkey (Türkiye)

Condition Browse Module

MeSH Terms

ID	Term
D050197	Atherosclerosis
D002340	Carotid Artery Diseases
D007674	Kidney Diseases

Ancestor Terms

ID	Term
D001161	Arteriosclerosis
D001157	Arterial Occlusive Diseases
D014652	Vascular Diseases
D002318	Cardiovascular Diseases

Browse Leaves

Not provided

Browse Branches

Not provided