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The study hypothesized that a narrow gastric conduit(less than 3cm in width) would minimize anastomotic leakage following minimally invasive esophagectomy. Therefore we raise this random-controlled research, and investigate the leakage ratio from different widths of gastric conduit formed during the operation.
Patients underwent minimally invasive esophagectomy in Zhongshan Hospital of Fudan University will be enrolled and be assigned to wide or narrow gastric conduit group randomly. Intra-operative blood supply and vascular SaO2 will be observed during the operation, and the rate of anastomotic leakage, together with its clinical details will be recorded in the two groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Narrow Gastric Conduit | Experimental | The group in which narrowed gastric conduit will be performed during minimally invasive esophagectomy |
|
| Wide Gastric Conduit | Experimental | The group in which widened gastric conduit will be performed during minimally invasive esophagectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Narrowed Gastric Conduit | Procedure | The gastric conduit will be formed much narrower in the intervention arm during minimally invasive esophagectomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| The anastomotic leakage rate | The anastomotic leakage is a severe complication following minimally invasive esophagectomy. The definition of anastomotic leakage is determined as per the STS (SOCIETY OF THORACIC SURGEONS) database. | the anastomotic leakage of participants will be followed for the duration of hospital stay, an expected average of 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yaxing Shen, MD | Contact | 86-13661983366 | SHEN.YAXING@ZS-HOSPITAL.SH.CN |
| Name | Affiliation | Role |
|---|---|---|
| Lijie Tan, MD | Fudan University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Division of Thoracic Surgery, Zhongshan Hospital of Fudan University | Recruiting | Shanghai | 200032 | China |
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| ID | Term |
|---|---|
| D057868 | Anastomotic Leak |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Widened Gastric Conduit | Procedure | A widened gastric tube will be formed during the surgery |
|
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