Left Atrial Appendage (LAA) Occluders After Catheter Ablation of Atrial Fibrillation

Implantation of Left Atrial Appendage Occluders Concomitantly With Catheter Ablation in Patients With Atrial Fibrillation

The primary objective of this study is to assess combined end point (All stroke, Systemic embolism, Cardiovascular death) between two groups.

Inclusion Criteria:

• Patient has paroxysmal, persistent or permanent non-valvular atrial fibrillation (AF)
• Eligible for long term warfarin
• CHADS score >= 1 (congestive heart failure [CHF], history of high blood pressure, 75 years of age or older, diabetes, prior stroke or transient ischemic attack [TIA])

Exclusion Criteria:

• Contraindicated for warfarin
• Contraindicated for aspirin or clopidogrel (Plavix)
• CHF Class 4
• Implanted mechanical valve
• Atrial septal or Patent Foramen Ovale (PFO) device
• Platelets < 100,000 or hemoglobin < 10
• Left ventricular ejection fraction (LVEF) < 30%