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| ID | Type | Description | Link |
|---|---|---|---|
| K01AA019694 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Alcoholic Beverage Medical Research Foundation | OTHER |
| National Institute on Alcohol Abuse and Alcoholism (NIAAA) | NIH |
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Tertiary Health Research Intervention Via Email (THRIVE; Kypri et al., 2009), originally utilized with Australian students, is unique in that it contains efficacious components derived from motivational interviewing (e.g., personalized feedback) and cognitive behavioral therapy (protective behavioral strategies), yet is very brief and has established efficacy. This study aims to test versions of THRIVE tailored to American college students. In addition to replicating original results with THRIVE, we will also test versions containing unique subsets of protective behavioral strategies to reduce alcohol consumption. The primary hypothesis is that versions of THRIVE will be associated with lower overall alcohol consumption than an assessment and brief brochure control condition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| THRIVE replication | Experimental | Participants in this condition receive THRIVE with a full list of direct and indirect protective behavioral strategies to reduce alcohol consumption. |
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| THRIVE direct strategies | Experimental | Participants in this condition receive THRIVE including a subset of protective behavioral strategies that are directly related to alcohol drinking. |
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| THRIVE indirect strategies | Experimental | Participants in this condition receive THRIVE including a subset of protective behavioral strategies that are indirectly related to alcohol drinking. |
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| Brief brochure and assessment control | Sham Comparator | Participants will answer the same survey questions as participants in the THRIVE conditions, but will receive a brief alcohol-related brochure with only didactic content rather than the intervention components received by participants randomized to THRIVE conditions. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| THRIVE | Behavioral | THRIVE stands for (Tertiary Health Research Intervention Via Email). Participants complete questions related to demographics and their alcohol use and receive brief personalized feedback based on this information, in addition to protective behavioral strategies, facts about alcohol and information about available resources to reduce their alcohol use. |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of alcohol use | 1-month post-intervention | |
| Protective behavioral strategy use | 1-month post-intervention | |
| Overall Weekly Alcohol Consumption | 1-month post-intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of heavy drinking days | 1-month post-intervention | |
| Frequency of alcohol use | 6-months post-intervention | |
| Overall weekly alcohol consumption |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Robert F Leeman, Ph.D. | Yale University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yale University School of Medicine | New Haven | Connecticut | 06519 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39146062 | Derived | Frohe T, Gebru NM, Wilson B, Leeman RF. Is a very brief web-based intervention with focus on protective behavioral strategies efficacious in reducing impaired control over alcohol in undergraduates? Exp Clin Psychopharmacol. 2025 Feb;33(1):1-7. doi: 10.1037/pha0000737. Epub 2024 Aug 15. |
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| ID | Term |
|---|---|
| D000428 | Alcohol Drinking |
| D040261 | Harm Reduction |
| ID | Term |
|---|---|
| D004327 | Drinking Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D009538 | Nicotine |
| ID | Term |
|---|---|
| D012991 | Solanaceous Alkaloids |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011725 | Pyridines |
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| Brief brochure and assessment control | Behavioral |
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| 6-months post-intervention |
| D006573 |
| Heterocyclic Compounds, 1-Ring |