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| Name | Class |
|---|---|
| National Center for Complementary and Integrative Health (NCCIH) | NIH |
| University of California, San Diego | OTHER |
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The investigators are developing and then testing whether Mindfulness-Based Stress Reduction, a group-based instruction for increasing mindfulness, reduces anxiety and depressive symptoms and improves cognitive functioning in older adults.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mindfulness Based Stress Reduction | Experimental | All participants in this arm receive Mindfulness Based Stress Reduction (MBSR). |
|
| control | Active Comparator | All participants in this arm receive an attention control |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MBSR | Behavioral | Mindfulness-Based Stress Reduction |
| |
| Measure | Description | Time Frame |
|---|---|---|
| cognitive functioning | neuropsychological battery examining memory, executive functioning, and attention | approximately 2 months of study intervention |
| Measure | Description | Time Frame |
|---|---|---|
| mind-wandering | computerized task(s) of mind-wandering | 2 months of intervention |
| mindfulness | self-report plus ecological momentary assessment measurements of mindfulness (process variable). |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eric Lenze, MD | Washington University School of Medicine | Principal Investigator |
| Julie Wetherell, PhD | University of California, San Diego | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California San Diego | San Diego | California | 92122 | United States | ||
| Washington University School of Medicine |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35476747 | Derived | Kornfield SL, Nicol GE, Lenze EJ, Yingling M, Loebach Wetherell J. Mindfulness-Based Stress Reduction in Older Individuals: Who Benefits the Most? Adv Mind Body Med. 2022 Winter;36(1):4-12. | |
| 32017250 | Derived | Haddad R, Lenze EJ, Nicol G, Miller JP, Yingling M, Wetherell JL. Does patient expectancy account for the cognitive and clinical benefits of mindfulness training in older adults? Int J Geriatr Psychiatry. 2020 Jun;35(6):626-632. doi: 10.1002/gps.5279. Epub 2020 Mar 20. |
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| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D003863 | Depression |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| control (health education) |
| Behavioral |
health education |
|
| 2 months of intervention |
| anxiety and depressive symptoms | scales of self-report anxiety and depressive symptoms from NIH PROMIS, and worry severity (Penn State Worry Questionnaire Abbreviated). also we will examine ecological momentary assessment measurements of anxiety and depressive symptoms. | 2 months of intervention |
| St Louis |
| Missouri |
| 63110 |
| United States |
| 28686822 | Derived | Wetherell JL, Hershey T, Hickman S, Tate SR, Dixon D, Bower ES, Lenze EJ. Mindfulness-Based Stress Reduction for Older Adults With Stress Disorders and Neurocognitive Difficulties: A Randomized Controlled Trial. J Clin Psychiatry. 2017 Jul;78(7):e734-e743. doi: 10.4088/JCP.16m10947. |