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There was more benefit from the infusion arm compared to the bolus arm.
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NULL HYPOTHESIS • There is no difference in the incidence of hypoglycemia among preterms receiving either two hourly 10% dextrose boluses or 10% dextrose infusion by burettes during the 72 hours of admission in Special Care Unit- Mulago Hospital.
ALTERNATE HYPOTHESIS
• Use of two hourly 10% dextrose boluses increases the incidence of hypoglycemia by 30% compared to 10% dextrose infusion by burettes among preterms admitted to Special Care Unit in the first 72 hours of admission.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bolus arm | Placebo Comparator | two hourly dextrose boluses administered via an intravenous cannula |
|
| infusion | Experimental | 10% dextrose infusion by burettes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 10% dextrose | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence proportion of hypoglycemia | 3months |
| Measure | Description | Time Frame |
|---|---|---|
| survival measured as a proportion | 3months |
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Inclusion Criteria:
- SELECTION CRITERIA Inclusion criteria
Exclusion Criteria
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mulago Hospital | Kampala | Mulago | +256 | Uganda |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25352865 | Derived | Kutamba E, Lubega S, Mugalu J, Ouma J, Mupere E. Dextrose boluses versus burette dextrose infusions in prevention of hypoglycemia among preterms admitted at Mulago Hospital: an open label randomized clinical trial. Afr Health Sci. 2014 Sep;14(3):502-9. doi: 10.4314/ahs.v14i3.2. |
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| ID | Term |
|---|---|
| D005947 | Glucose |
| ID | Term |
|---|---|
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |
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