Not provided
Not provided
Not provided
Not provided
Data analysis issue
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of the investigators study is to demonstrate the association between fetal cardiac rhythm abnormalies after epidural analgesia and the maternal systemic transfer of ropivacaine and/or sufentanil.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| fetal cardiac rhythm abnormally | Other | patient at term, in spontanous labor with fetal cardiac rythm abnormally which occurs 30 minutes after the epidural analgesia induction |
|
| control group | Other | patient at term, spontaneous labor, without any fetal cardiac rhythm abnormalies during the 30 minutes after the epidural analgesia induction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ropivacaine | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasmatic concentrations compared maternal ropivacaine based on the presence of abnormal fetal heart rate | Maternal Plasmatic concentrations of ropivacaine will be measured in mg / liter of maternal blood and the median of each group will be compared by paired Wilcoxon test | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Plasmatic concentrations compared maternal sufentanil based on the presence of abnormal fetal heart rate | Maternal Plasmatic concentrations of sufentanil will be measured in mg / liter of maternal blood and the median of each group will be compared by paired Wilcoxon test | 1 day |
Not provided
Inclusion Criteria:
18 years old or more
nulliparous
_ one fetus
head first
spontaneous labor
epidural analgesia
no fetal cardiac rhythm abnormalies before the epidural analgesia
no active management of labor during 30 minutes after the epidural analgesia induction
at term
signature of the consent form
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| centre hospitalier universitaire de Rouen, Hopital Charles Nicolle | Rouen | 76000 | France |
Not provided
| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| D000588 |
| Amines |