Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
We aim to test the hypothesis that fluid therapy based on pulse pressure variation (PPV) in patients after cardiac surgery who are mechanically ventilated leads to a significant decrease in the amount of fluid given to such patients in the first 24 hours after surgery
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PPV | Active Comparator | use PPV to guide fluid therapy |
|
| standard care | Placebo Comparator | fluids according to standard care |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| IV fluid according to PPV | Other | intravenous fluids |
| |
| fluids according to standard care |
| Measure | Description | Time Frame |
|---|---|---|
| Mean amount of fluid given in the first 24 hours after surgery | all intravenous fluid administered | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Physiological outcome | Blood lactate | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Physiological outcome | cardiac index | 24 hours |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Austin Hospital | Melbourne | Victoria | 3079 | Australia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25220528 | Derived | Suzuki S, Woinarski NC, Lipcsey M, Candal CL, Schneider AG, Glassford NJ, Eastwood GM, Bellomo R. Pulse pressure variation-guided fluid therapy after cardiac surgery: a pilot before-and-after trial. J Crit Care. 2014 Dec;29(6):992-6. doi: 10.1016/j.jcrc.2014.07.032. Epub 2014 Aug 7. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Other |
|