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| ID | Type | Description | Link |
|---|---|---|---|
| PRIMEBOND21 | Registry Identifier | Primebond |
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The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
Adhesive systems based on total etch technique remains the most popular products among dental practitioners. These systems are based on the use of an acid conditioner to remove the smear layer and demineralize the enamel and dentin. After the removal of the conditioner by rinsing, a mixture containing the primer and adhesive - i.e. one bottle adhesives - is applicated over the demineralized tissues. The polymerization of the adhesive monomers into microporosities created by acid conditioning forms the structure knowing as hybrid layer or resin-dentin interdifusion zone. A common problem related to total etch technique is the incomplete infiltration of adhesive monomers through demineralized dentin, resulting in the presence of a zone of unprotected collagen fibrils beneath the hybrid layer that is prone to enzymatic degradation. According to some laboratory studies, consecutive application of multiple adhesive coats results in quantitative and qualitative improvements in dental adhesion. In addition to increasing the values of bond strength to dentin, consecutive application of multiple adhesive layers enhances the infiltration of adehesive monomers through demineralized dentin, resulting in a more homogenous hybrid layer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Three adhesive coats | Experimental | Consecutive application of three one-bottle adhesive coats |
|
| Two adhesive coats | Active Comparator | Consecutive application of two one-bottle adhesive coats |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Three adhesive coats | Procedure | After caries removal, enamel margins will be conditioned with phosphoric acid gel 37% by 15 seconds and dentin walls by 8 seconds. The etchant will be removed with use of water spray by 30 seconds. The water excess will be removed with a cotton pellet. The first layer of Prime & Bond 2.1 adhesive will be applied with a microbrush. After 20 seconds a second layer will be applied and after a similar period a third layer will be applied over cavity walls. Again, after 20 seconds, the layers will be gently air-dried and photopolymerized by 10 seconds with a LED photoactivation unit. |
| Measure | Description | Time Frame |
|---|---|---|
| Survival rate | Survival rate considering failure of restorations due: partial or complete loss of restorative material; marginal ditching; superficial or marginal discoloration; secondary caries; pulpal complications; wear of restorative material; tooth fracture. | 06, 12, 18, 24, 30 and 36 months |
| Measure | Description | Time Frame |
|---|---|---|
| Marginal adaptation | Evaluation of resin replicas of restored teeth on scanning electron microscopy (SEM) | 06, 12, 18, 24, 30 and 36 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marlus R Cajazeira, MsC | Contact | 55-21-8383-2492 | marlus.cajazeira@gmail.com | |
| Lucianne Cople Maia, PhD | Contact | 55-9994-3131 | rorefa@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Marlus RR Cajazeira, MsD | Universidade Federal do Rio de Janeiro | Principal Investigator |
| Lucianne Cople Maia, PhD | Universidade Federal do Rio de Janeiro | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Dentistry of Federal University of Rio de Janeiro | Recruiting | Rio de Janeiro | Rio de Janeiro | 21941-617 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15279481 | Background | Hashimoto M, Sano H, Yoshida E, Hori M, Kaga M, Oguchi H, Pashley DH. Effects of multiple adhesive coatings on dentin bonding. Oper Dent. 2004 Jul-Aug;29(4):416-23. | |
| 15159072 | Background | Hashimoto M, De Munck J, Ito S, Sano H, Kaga M, Oguchi H, Van Meerbeek B, Pashley DH. In vitro effect of nanoleakage expression on resin-dentin bond strengths analyzed by microtensile bond test, SEM/EDX and TEM. Biomaterials. 2004 Nov;25(25):5565-74. doi: 10.1016/j.biomaterials.2004.01.009. |
| Label | URL |
|---|---|
| School of Dentistry of Federal University of Rio de Janeiro web site | View source |
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| Two adhesive coats | Procedure | After caries removal, enamel margins will be conditioned with phosphoric acid gel 37% by 15 seconds and dentin walls by 8 seconds. The etchant will be removed with use of water spray by 30 seconds. The water excess will be removed with a cotton pellet. The first layer of Prime & Bond 2.1 adhesive will be applied with a microbrush. After 20 seconds a second layer will be applied and after 20 seconds, the layers will be gently air-dried by 5 seconds. The two layers will be photopolymerized by 10 seconds with a LED photoactivation unit. |
|
| Eduardo M da Silva, PhD |
| Universidade Federal Fluminense |
| Study Chair |
| Alessandro D Loguércio, PhD | Universidade Estadual de Ponta Grossa | Study Chair |
| Michelle M Amari, MsD | Universidade Federal Fluminense | Study Director |
| 19904824 | Background | Hashimoto M. A review--micromorphological evidence of degradation in resin-dentin bonds and potential preventional solutions. J Biomed Mater Res B Appl Biomater. 2010 Jan;92(1):268-80. doi: 10.1002/jbm.b.31535. |
| 14981122 | Background | Pashley DH, Tay FR, Yiu C, Hashimoto M, Breschi L, Carvalho RM, Ito S. Collagen degradation by host-derived enzymes during aging. J Dent Res. 2004 Mar;83(3):216-21. doi: 10.1177/154405910408300306. |
| 11820372 | Background | Hashimoto M, Ohno H, Kaga M, Sano H, Endo K, Oguchi H. The extent to which resin can infiltrate dentin by acetone-based adhesives. J Dent Res. 2002 Jan;81(1):74-8. doi: 10.1177/002203450208100116. |
| ID | Term |
|---|---|
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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