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| ID | Type | Description | Link |
|---|---|---|---|
| 2012-A00044-39 | Other Identifier | IDRCB |
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This clinical trial aims to compare morbidity and cost associated with acute attacks of hereditary angioedema in patients with an intervention based on a support after a phone call to the call center (SOS HAE) from a group of patients does not change their practice.
Investigators propose a study to determine whether a call center for an acute attack of HAE associated with intervention recommendations based on systematic early treatment (self-administration at home or by a caregiver) would reduce the morbidity and the socioeconomic impact.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1: phone to call center | Experimental | recommendations to phone to the call center for all the patients who have an acute attack |
|
| 2: usual strategy | No Intervention | usual strategy. No intervention (patients does not change their practice) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| phone to the call center | Other | recommendations to phone to the call center for all the patients who have an acute attack |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of hospital admissions for angioedema attack- no (%) | at 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Number of ICU admissions - no (%) | at 2 years | |
| Number of ED admissions - no (%) | at 2 years | |
| Number of hospital admissions for others causes - no (%) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Frédéric ADNET, MD,PhD | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SAMU 93 - Hôpital Avicenne | Bobigny | Île-de-France Region | 93000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31109849 | Derived | Javaud N, Altar A, Fain O, Reuter PG, Desmaizieres M, Petrovic T, Ghazali A, Durand-Zaleski I, Bouillet L, Vicaut E, Launay D, Martin L, Floccard B, Gompel A, Sobel A, Boccon-Gibod I, Kanny G, Lapostolle F, Adnet F. Hereditary angioedema, emergency management of attacks by a call center. Eur J Intern Med. 2019 Sep;67:42-46. doi: 10.1016/j.ejim.2019.05.007. Epub 2019 May 18. | |
| 29503044 |
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| ID | Term |
|---|---|
| D054179 | Angioedemas, Hereditary |
| ID | Term |
|---|---|
| D000799 | Angioedema |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D000081208 | Hereditary Complement Deficiency Diseases |
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| at 2 years |
| Number of intubations - no (%) | at 2 years |
| Number of EMS interventions - no (%) | at 2 years |
| Number of working days lost | at 2 years |
| Mortality - no (%) | at 2 years |
| Mortality for angioedema attack- no (%) | at 2 years |
| Cost of angioedema attacks | at 2 years |
| Derived |
| Javaud N, Fain O, Durand-Zaleski I, Launay D, Bouillet L, Gompel A, Sobel A, Woimant M, Rabetrano H, Petrovic T, Lapostolle F, Boccon-Gibod I, Reuter PG, Bertrand P, Mezaour M, Coppere B, Floccard B, Kanny G, Baker E, Martin L, Vicaut E, Adnet F. Specialist Advice Support for Management of Severe Hereditary Angioedema Attacks: A Multicenter Cluster-Randomized Controlled Trial. Ann Emerg Med. 2018 Aug;72(2):194-203.e1. doi: 10.1016/j.annemergmed.2018.01.053. Epub 2018 Mar 2. |
| 27140403 | Derived | Javaud N, Fain O, Durand-Zaleski I, Launay D, Bouillet L, Gompel A, Sobel A, Woimant M, Rabetrano H, Petrovic T, Lapostolle F, Boccon-Gibod I, Reuter PG, Bertrand P, Coppere B, Floccard B, Kanny G, Martin L, Vicaut E, Adnet F. Dedicated call center (SOS-HAE) for hereditary angioedema attacks: study protocol for a randomised controlled trial. Trials. 2016 Apr 30;17(1):225. doi: 10.1186/s13063-016-1350-0. |
| D000081207 | Primary Immunodeficiency Diseases |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D014581 | Urticaria |
| D017445 | Skin Diseases, Vascular |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D007153 | Immunologic Deficiency Syndromes |