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| ID | Type | Description | Link |
|---|---|---|---|
| s-04058c | Registry Identifier | The National Committees for Research Ethics in Norway |
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Background. Do pressure dependent tracheal obstructions (PDTO) often seen during bronchoscopy in COPD patients affect pulmonary function tests and breathing symptoms? Method. Model study. A garden hose was compressed from one side to simulate the posterior wall of the trachea bulging into the lumen. For two obstruction lengths - 3 cm and 12 cm, the hose was increasingly compressed in eight steps. Resistance was measured at each step for airflows 1 l/s through 9 l/s, and digital photos of the luminal area were taken which were used by a computer to estimate the cross sectional area reduction and the corresponding distance between the bulging (posterior)and the opposite (anterior) wall (AP-distance).
Patient study. 104 stable COPD patients studied by pulmonary function tests and bronchoscopy. The tracheal obstruction was observed during forced expiration and cough, and the cross sectional area reduction was estimated using the results from the model study.
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Inclusion Criteria:
Exclusion Criteria:
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Patients (both sexes) in a pulmonary rehabilitation clinic
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| Name | Affiliation | Role |
|---|---|---|
| Ivar Ellingsen, Dr med | LHL Helse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Glittreklinikken | Hakadal | Akershus | 1485 | Norway |
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| ID | Term |
|---|---|
| D055089 | Tracheobronchomalacia |
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D000402 | Airway Obstruction |
| ID | Term |
|---|---|
| D002357 | Cartilage Diseases |
| D009140 | Musculoskeletal Diseases |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
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| D014133 | Tracheal Diseases |
| D009139 | Musculoskeletal Abnormalities |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012131 | Respiratory Insufficiency |
| D012120 | Respiration Disorders |