Genetic transition is important in the etiology of bipolar disorder (BD). So, evaluation of children of BD parents and diagnosed with and BD children whether or not brain has affected zones. These groups were compared to healthy controls and whether or not the mental health of children is influenced will be evaluated by the clinical investigation.

MRI studies in children at risk of BD, our understanding of the neurobiology of BD and abnormalities in the studied regions, regions that predispose to the development of our understanding of PBB will shed light on the etiology of the disorder. In this study, the cranial MRI findings and clinical features in adolescents with bipolar disorder and the same age and sex matched children who have parents with BD and healthy controls were investigated. Since there is few studies that evaluate these three groups, there is a need to increase our knowledge on this issue.

Inclusion Criteria:

• Children with BD between the ages of 12-18
• Parents with BD who have children between the ages of 12-18
• Healthy children whose parents do not have BD
• Patients who does not have mental or organic disability to answer the questions
• Graduated from primary school

Exclusion Criteria:

• Patients who have mental or organic disability to answer the questions
• Patients who have a history of any chronic disease which is likely to affect the central nervous system
• Patients who have a contraindication for any first application for Magnetic Resonance Imaging (MRI)

In this study, the cranial MRI findings and clinical features in adolescents with bipolar disorder and the same age and sex matched children who have parents with BD and healthy controls were investigated.