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| ID | Type | Description | Link |
|---|---|---|---|
| C0038345 | Other Grant/Funding Number | The Small & Medium Business Administration |
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The aim of our study is to investigate the effects of high-protein diet on satiety and incretin hormones in patients with diabetes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High-protein diet | Experimental |
| |
| Standard diet | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High-protein diet | Dietary Supplement | The high-protein diet is made up of 50% carbohydrate, 40% of protein and 10% of fat, providing 480 kcal. A protein part of the high-protein diet is mostly composed of a grilled Jeju red horsehead fish, a special product of Jeju island in Korea. |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in the incremental area under the curve (iAUC) for peptide YY (PYY) after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in the iAUC for cholecystokinin (CCK) after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
| Difference in the iAUC for ghrelin after food ingestion between high-protein and standard diet groups |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in the iAUC for glucose after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
| Difference in the iAUC for insulin after food ingestion between high-protein and standard diet groups |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gwanpyo Koh, Professor | Jeju National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jeju National University Hospital | Jeju City | 690-767 | South Korea |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| D000073600 | Diet, High-Protein |
| ID | Term |
|---|---|
| D004035 | Diet Therapy |
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
| D004032 | Diet |
| D009747 |
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|
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| Standard diet | Dietary Supplement | The standard diet is made up of 60% carbohydrate, 20% of protein and 20% of fat, providing 480 kcal. |
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Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. |
| 3 hours |
| Difference in the iAUC for glucagon-like peptide 1 (GLP-1) after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
| Difference in the iAUC for glucose-dependent insulinotropic polypeptide (GIP) after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. |
| 3 hours |
| Difference in the iAUC for C-peptide after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
| Difference in the iAUC for glucagon after food ingestion between high-protein and standard diet groups | Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced. | 3 hours |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |