Study on Evaluating the Promote Effect of Yili Mei Yi Tian Active Lactobacillus Drink on Immunity and Physical Intestinal Canal

Inclusion Criteria:

• Age 25 to 45 years sub-health white-collars, catch cold for 4 to 6 times in last year, with low immunity;
• Non-specific and/or moderate constipation;
• Irregular or occasional gastrointestinal disorders (flatulence, gurgling, feeling heavy after eating, abdominal pain);
• Slow transit or irregular bowels movements (abnormal feces solidity, bowel movements decreased, e.g. every 2-3 days or less than 3 times per week);
• Able to understand the nature and purpose of the study including potential risks and side effects;
• Willing to consent to study participation and to comply with study requirements

Exclusion Criteria:

• Diagnosed as immunity-low associated with chronic disease;
• Diagnosed as chronic constipation;
• Treated gastrointestinal symptoms;
• Currently suffering from diarrhea;
• Suffering from rhinitis chronic, laryngitis, labored breathing that similar to flu symptoms. Such as chronic allergic rhinitis, asthma, COPD;
• Treatment by analgesic such as aspirin and paracetamol;
• Had laxatives or other remedies to promote digestion 2 weeks prior to the study start;
• Consuming dairy products or supplements containing pro/pre-biotic 10 days prior to the study start;
• Long-term use of any prescription or OTC medication that inhibit or prevent flu symptoms, including but not limited to, antihistamine, pectoral, high doses of vitamin C;
• Recent use (within 3 months of screening) of any prescription or OTC medication that significantly affects immune response, such as antibiotic;
• Recent inoculation (within 6 months of screening) of influenza vaccine, or other vaccine in 15 days;
• History of alcohol, drug, or medication abuse;
• Pregnant or breastfeeding women;
• Participation in another study with any investigational product within 3 months of screening
• Any comorbidity that could, in the opinion of the investigator, preclude the subject's ability to successfully and safely complete the study or that may confound study outcomes