Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to determine whether Yili Lactoferrin ShuHua Milk are effective in reducing the occurrence of flu symptoms.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yili Lactoferrin ShuHua Milk (lactoferrin 5mg/100ml) | Active Comparator | Total 250mL milk (with lactoferrin 5mg/100ml) will be taken once per day at 10am daily during the 84 days intervention. |
|
| Yili Lactoferrin ShuHua Milk (lactoferrin 10mg/100ml) | Active Comparator | Total 250mL milk (with lactoferrin 10mg/100ml) will be taken once per day at 10am daily during the 84 days intervention. |
|
| Recombined low-protein milk | Placebo Comparator | Total 250mL placebo milk will be taken once per day at 10am daily during the 84 days intervention. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yili Lactoferrin ShuHua Milk (Lactoferrin 5mg/100ml) | Dietary Supplement | Total 250mL milk (with lactoferrin 5mg/100ml) will be taken once per day at 10am daily during the 84 days intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Assess occurrence of flu symptoms during intervention | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Assess severity of flu symptoms | 3 months | |
| Proportion of subjects which require treatment with flu medication | 3 months | |
| Change in immune markers such as antibodies and interleukins |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Ying An, Ph.D | Inner Mongolia Hilo Industrial Group Co., Ltd | Study Director |
| Donglian Cai | Changhai Hospital of Shanghai, Nutriology Dept. | Principal Investigator |
| Yeqing Shi | Changhai Hospital of Shanghai, Rheumatology Dept. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NanMoFang Community Health Service Center | Chao Yang District | Beijing Municipality | China | |||
| JuQuan Community Health Service Center |
Not provided
Not provided
Not provided
Not provided
Not provided
| Yili Lactoferrin ShuHua Milk (Lactoferrin 10mg/100ml) | Dietary Supplement | Total 250mL milk (with lactoferrin 10mg/100ml) will be taken once per day at 10am daily during the 84 days intervention. |
|
| Recombined low protein milk | Dietary Supplement | Total 250ml of placebo milk will be taken once a day at 10am daily during the 84 day intervention. |
|
| Baseline & 3 months |
| Record subject sick leave due to flu | 3 months |
| GuCun, Baoshan District, |
| Shanghai Municipality |
| China |
| ID | Term |
|---|---|
| D007251 | Influenza, Human |
| D003139 | Common Cold |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D009976 | Orthomyxoviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012140 | Respiratory Tract Diseases |
| D010850 | Picornaviridae Infections |
Not provided
Not provided
| ID | Term |
|---|---|
| D007781 | Lactoferrin |
| ID | Term |
|---|---|
| D012697 | Serine Endopeptidases |
| D010450 | Endopeptidases |
| D010447 | Peptide Hydrolases |
| D006867 | Hydrolases |
| D004798 | Enzymes |
| D045762 | Enzymes and Coenzymes |
| D057057 | Serine Proteases |
| D006023 | Glycoproteins |
| D006001 | Glycoconjugates |
| D002241 | Carbohydrates |
| D061250 | Transferrins |
| D033862 | Iron-Binding Proteins |
| D002352 | Carrier Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D007782 | Lactoglobulins |
| D000067816 | Whey Proteins |
| D008894 | Milk Proteins |
| D000080224 | Animal Proteins, Dietary |
| D004044 | Dietary Proteins |
| D005916 | Globulins |
| D008667 | Metalloproteins |
Not provided
Not provided