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Osteoporosis is the most common disease of bone and characterized firstly by low bone mass and secondly, impaired bone microarchitecture structure resulting in reduced strength and increased risk of fracture. Osteoporosis is divided into: primary (Postmenopausal Osteoporosis Osteoporosis & elderly and senile osteoporosis) and secondary. The most common form is postmenopausal osteoporosis. It occurs in women after menopause and is associated with decreased estrogen production, which normally occurs at this age women Osteoporosis usually occurs after age 50, it is very common in women than in men, and its frequency increases with advancing age.
According to the findings of epidemiological studies in different countries, osteoporosis affects 25-35% of women and 15-20% of men aged 50 and over. In terms of our country in the recent nation-epidemiological research on rheumatic diseases in the general adult population, ie persons aged 19 and over, organized and conducted by the Greek Institute of Rheumatology Research, became a separate study on frequency of osteoporosis in women aged 50 years and above. These women was measured BMD at the lumbar spine and at the upper end of the femur and found that 28.4% of Greek women aged 50 and over have osteoporosis. It is indeed very interesting finding in this study that women who have osteoporosis, the vast majority, ie about 75%, I do not know. This is of particular importance and highlights the need to educate and inform systematically the public, especially women regarding both the modern possibilities for early diagnosis of osteoporosis, and for the implementation of primary and secondary prevention.
Osteoporosis is a major public health problem for two reasons: First, because it is common, and secondly because it has significant impact on patients and their families, the health system and the national economy.
The main clinical manifestation of osteoporosis is fractures low energy, ie fractures occurring after mild degree injury, eg fall from a standing position. Approximately 40% of cases osteoporotic fractures on the vertebrae, 20% in the femoral neck, 20% to 20% radius and several other bones. While osteoporosis is generally regarded as a disease of women, however, as already mentioned above, osteoporosis affects and men. It has even been found that 30% of osteoporotic fractures of the femoral neck and 20% of osteoporotic vertebral fractures occur in men.
The risk of fractures of the hip, vertebrae and radius increases with advancing age in both women and men. It has even been estimated that the risk of osteoporotic fracture in women aged 50 and over is 40-50% and 15-20% in men.
The adverse effects of osteoporosis patients and their families, the health system and the national economy due to fractures. Indicative only some of these effects:
Moreover, in 2000 the European Union the then 15 Member States (total population of 379,000,000 people) is estimated to have occurred 3.79 million osteoporotic fractures and that the direct costs of these fractures (costs of hospitalization, surgery and medical care) was approximately 32 billion Euros.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| All measurements | Total measured population |
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| Measure | Description | Time Frame |
|---|---|---|
| Osteoporosis Indicator | T-score per female as measured by Holofic Sahara Instrument | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Postmenopausal females screened for osteoporosis
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| Name | Affiliation | Role |
|---|---|---|
| Aristeidis Kerasiotis, Endocrinologist | Director of Endocrinology Unit ,'Iaso' Hospital of Athens, 37-39 Kifisias avenue, 15123, Athens, Greece | Study Chair |
| Ioannis Lentzas, MD | Director, Medical State Center, Simopoulo, Perfecture of Ilia | Principal Investigator |
| Dimitrios Tsorntanidis, MD | Registrat B', Medical State Center, Erymantheia, Achaia Perfecture | Principal Investigator |
| Maria Chronopoulou, MD | Registrat B', Medical State Site, Diakofto, Achaia Perfecture | Principal Investigator |
| Olimpia Raftopoulou, MD | Registrat B', Medical State Site, Myrsini, Perfecture of Ilia | Principal Investigator |
| Stylianos Danelakis, GP | Medical State Site, Leontari | Principal Investigator |
| Thomas Simos, GP | Medical State Site, Anavra | Principal Investigator |
| Theofanis Tsirogiannis, GP | Medical State Site, Agnantero | Principal Investigator |
| Konstantinos Vatalis, GP |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Iaso Hospital of Athens, Center of Endocrinology and Bone Metabolism | Athens | Kifisias Avenue, 37-39, Maroussi | 15123 | Greece |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 7696835 | Background | Kanis JA. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int. 1994 Nov;4(6):368-81. doi: 10.1007/BF01622200. | |
| Background | McClung M. Difference in Distribution of T-scores Among Bone Density Tests in Postmenopausal Women. Bone Vol. 23, (5S), pg. S193, 1998. | ||
| 12200654 |
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| ID | Term |
|---|---|
| D010024 | Osteoporosis |
| D001851 | Bone Diseases, Metabolic |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Medical State Site, Tsartsani |
| Principal Investigator |
| Ioannis Antonopoulos, GP | Medical State Site, Ampelonas | Principal Investigator |
| Labros Kontovos, GP | Medical State Site, Nikaia, Perfecture of Larisa | Principal Investigator |
| Chara Kalliora, GP | Medical State Site, Gomfon, Perfecture of Trikala | Principal Investigator |
| Athanasios Misios, GP | Medical State Site, Megala Kalyvia | Principal Investigator |
| Antonis Monastiriotis, GP | Medical State Site, Oropos - Chalkoutsi | Principal Investigator |
| Zeppos Monstratos, GP | Medical State Site, Marathonas | Principal Investigator |
| George Sakellaropoulos, Orthop. | Medical State Site, Marathonas | Principal Investigator |
| Andreas Sotiriou, Orthop. | Private Office, Zografou, Athens | Principal Investigator |
| Maria Degaiti, GP | Medical State Site, Ano Mera, Island of Mykonos | Principal Investigator |
| Aristeidis Frydas, Medical Internist | Director, Medical State Center, Plomari, Island of Lesvos | Principal Investigator |
| Nikolaos Tsamouras, GP | Medical State Center, Agiassos, Island of Lesvos | Principal Investigator |
| Ioannis Komninos, GP | Medical State Center of Neapolis | Principal Investigator |
| Nikolaos Tsakountakis, GP | Medical State Center of Kastelli, Creta Island | Principal Investigator |
| Emmanouel Paterakis, GP | Private Madical Office, Heraklion, Creta Island | Principal Investigator |
| Panagiota Gourgoulia, MD | Regional State Medical Center of Giannouli - Tyrnavos, Perfecture of Larisa, Greece | Principal Investigator |
| Zisis Kelepouris, GP | Regional State Medical Center Platanos-Raxa, Perfecture of Trikala, Greece | Principal Investigator |
| Christos Ganochoritis, GP | Medical State Center of Pyrgetos and Egani, Regional Perfecture of Larisa | Principal Investigator |
| Demetra Zambouka, GP | Medical State Center of Agioi Anargyri, Regional Perfecture of Larisa | Principal Investigator |
| Charalampos Terzopoulos, MD, Orthopedics | Private office, Zografou, Athens, Greece | Principal Investigator |
| John Sakellariou, MD, Pathology, Registrat A | Medical Center of Farkadona, Thessalia, Greece | Principal Investigator |
| Aglaia Roganaki, MD, Registrat B, | Peripheral Medical Center of Mitropolis, Thessalia, Greece | Principal Investigator |
| Vasilis Delezos, MD, Registrat B | Medical Center of Sophades, Thessalia, Greece | Principal Investigator |
| Victoria Katsouri, MD, Registrat B | Medical Center of Sophades, Thessalia, Greece | Principal Investigator |
| Maria Papala, MD | State Medical Center of Tyrnavos, Thessalia, Greece | Principal Investigator |
| Styliani Papakosta, MD, Phyciatry | Medical Private Office, Larisa, Greece | Principal Investigator |
| Athanasios Tsivgoulis, MD in Physiatry | Medical Diagnosis Center, Lesvos Island, Greece | Principal Investigator |
| Petros Prokopis, MD | Medical Office of Avlona | Principal Investigator |
| George Papadimitriou, MD, Orthopedics | Private Medical Office, Vari Attikis | Principal Investigator |
| Vasilios Hamos, MD, Director | State Medical Cener, Agia, Larissa | Principal Investigator |
| Lemonia Arvanitakou, MD | State Medical Center, Agia, Larissa | Principal Investigator |
| Victoria Rizou, MD | State Medical Office, Halki, Larissa | Principal Investigator |
| Vassiliki Mamakou, MD, Internist | Mytilini | Principal Investigator |
| Antonios Partsinevelos, MD, Orth | Private Office, Marousi, Athens | Principal Investigator |
| George Patoulis, MD, Orth | Private Office, Marousi, Athens | Principal Investigator |
| Background |
| Ikeda Y, Iki M, Morita A, Aihara H, Kagamimori S, Kagawa Y, Matsuzaki T, Yoneshima H, Marumo F; JPOS Study Group. Age-specific values and cutoff levels for the diagnosis of osteoporosis in quantitative ultrasound measurements at the calcaneus with SAHARA in healthy Japanese women: Japanese population-based osteoporosis (JPOS) study. Calcif Tissue Int. 2002 Jul;71(1):1-9. doi: 10.1007/s00223-001-2079-6. Epub 2002 Jun 20. |
| 15241583 | Background | Magkos F, Manios Y, Babaroutsi E, Sidossis LS. Quantitative ultrasound calcaneus measurements: normative data for the Greek population. Osteoporos Int. 2005 Mar;16(3):280-8. doi: 10.1007/s00198-004-1670-x. Epub 2004 Jul 6. |