Pathogenesis of Functional Hypothalamic Amenorrhea

Pathogenesis of Functional Hypothalamic Amenorrhea

This is a randomized pilot study of the use of cognitive behavior therapy versus observation to treat functional hypothalamic amenorrhea, often termed stress-induced anovulation.

The study enrollment was completed in 2003. The study results are being analyzed.

Inclusion Criteria:

• women with functional hypothalamic amenorrhea
• day awake / night asleep schedule

Exclusion Criteria:

• eating disorders, depression, excessive exercise or any other cause of amenorrhea and anovulation other than functional hypothalamic amenorrhea
• weight loss greater than 10 pounds when amenorrhea developed
• running more than 10 miles per week or exercising more than 10 hours per week