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| Name | Class |
|---|---|
| Onze Lieve Vrouw Hospital | OTHER |
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In this study the investigators compare the usual way of embryo transfer (without medication) with an embryo transfer while administering oxytocine antagonist. This to improve implantation and increase the pregnancy rate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Atosiban | Active Comparator | Patients receive a bolus injection of 6.75mg atosiban and following an atosibaninfusion at 18mg/u during 3 hours. |
|
| placebo | Placebo Comparator | Patients receive a placebo bolus injection (NaCl 0.9%)and an infusion of NaCl 0.9% during 3 hours |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Atosiban | Drug | Bolus atosiban 6.75mg + infusion atosiban 18mg/u during 3 hours. once administered starting 1 hour before embryotransfer. |
|
| Measure | Description | Time Frame |
|---|---|---|
| implantation rate | the number of patients that show a positive serum blood pregnancy test | 16 days from eggretrieval |
| Measure | Description | Time Frame |
|---|---|---|
| pregnancy rate | The number of patients with an ongoing first trimester pregnancy | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AZ Jan Palfijn | Ghent | Oost-vlaanderen | 9000 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34467530 | Derived | Craciunas L, Tsampras N, Kollmann M, Raine-Fenning N, Choudhary M. Oxytocin antagonists for assisted reproduction. Cochrane Database Syst Rev. 2021 Sep 1;9(9):CD012375. doi: 10.1002/14651858.CD012375.pub2. |
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| ID | Term |
|---|---|
| C047046 | atosiban |
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| placebo | Drug |
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