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| Name | Class |
|---|---|
| University Hospital, Limoges | OTHER |
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Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal nerves innervating the breast. The aim of this study is to evaluate the efficacy of the PECBLOCK performed under echoguidance in minor and major breast surgery. The prevention of chronic pain following surgery will also be evaluated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PECBLOCK performed with bupivacaine | Active Comparator | Active drug given through PECBLOCK in these patients. |
|
| PECBLOCK performed with NaCl 0.9% | Placebo Comparator | Placebo drug given through PECBLOCK in these patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PECBLOCK under echoguidance | Procedure | Performance of block under echography |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain score at rest in the recovery room | Using a 0-10 verbal numerical scale where 0 is no pain and 10 the worst pain imaginable | 30 min after entering the recovery room or just before morphine administration if needed |
| Measure | Description | Time Frame |
|---|---|---|
| Total morphine consumption in the recovery room | When surgery is over and the patient is brought to the recovery room, the total morphine consumption in mg used in the recovery (for pain less than 4/10) is recorded | in the recovery room before discharge (after 1 h on average)) |
| Measure | Description | Time Frame |
|---|---|---|
| Total sufentanil consumption during surgery | When surgery is over, 1-2 h on average depending if it is a tumorectomy or a mastectomy, the total sufentanil consumption in micrograms during surgery is recorded. | at the end of surgery (1-2 h on average) |
| Assess any complication from PECBLOCK |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jérôme Cros, MD | CHU Limoges | Principal Investigator |
| Pierre Beaulieu, MD | CHUM | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHUM | Montreal | Quebec | H2W 1T8 | Canada | ||
| University Hospital, Limoges |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29672368 | Derived | Cros J, Senges P, Kaprelian S, Desroches J, Gagnon C, Labrunie A, Marin B, Crepin S, Nathan N, Beaulieu P. Pectoral I Block Does Not Improve Postoperative Analgesia After Breast Cancer Surgery: A Randomized, Double-Blind, Dual-Centered Controlled Trial. Reg Anesth Pain Med. 2018 Aug;43(6):596-604. doi: 10.1097/AAP.0000000000000779. |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D010146 | Pain |
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D011183 | Postoperative Complications |
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Cardiovascular collapse, anaphylactic shock, hematoma, bleeding..? |
| first 24 hours post surgery |
| Limoges |
| 87042 |
| France |
| D010335 | Pathologic Processes |