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| ID | Type | Description | Link |
|---|---|---|---|
| 216494 | Other Grant/Funding Number | MGH Orhtopaedic Department Funds 216494 |
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The specific aim is to quantify the stability of the acetabular and femoral components of a revision total hip arthroplasty (THA) in vivo as currently performed at our institution. In this way, the investigators will gain insight into the outcome of the current state of the art of revision arthroplasty surgery. In the past, acetabular and femoral component stability has been measured using radiostereometric analysis (RSA) and when patients having revision total hip operations were compared to patients undergoing primary total hip operations it was possible to determine differences in stability and this was predictive of the intermediate to long-term performance of the acetabular and femoral reconstruction. The investigators propose to use this established, high resolution technique to assess and compare the stability of the revision implants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Revision Total Hip | Experimental | patients recieving a revision total hip replacement will be assessed for implant stability and wear using RSA. Tantalum beads will be placed in the polyethylene and surrounding pelvic and femoral bone. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bead placement during revision hip replacement surgery | Procedure | Tantalum beads will be placed in the surrounding pelvic and femoral bone and the polyethylene component during surgical treatment of failed primary THA components |
| Measure | Description | Time Frame |
|---|---|---|
| Stability of Acetabular and femoral components | RSA films will be taken at the prescribed time intervals to measure component mothion over time. | 1, 2, 3, 5 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Wear of the polyethlene component | The movement of the femoral head into the polyethylenen, (wear), will be measured at the prescribed time intervals. | 1, 2, 3, 5 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment/questionaire HOOS | Hip disability and Osteoarthritis Outcome Score | Pre-op, 1, 2, 3, 5 years after surgery |
| Assessment/Questionaires Harris Hip Score | Hip specific questionaire |
Inclusion Criteria:
Exclusion Criteria:
Subjects with limited life span.
Subjects with difficulty in comprehending study protocol for any reason.
Subjects with complex disease entities which significantly increase the risks of the surgery such as any major platelet abnormality, hematological disorder, or any other major medical complication which could substantially reduce longevity, put them at further risk due to immunocompromisation or increase the risk of infection.
Female subjects that are pregnant or who may suspect they are pregnant or who plan to become pregnant while participating in this study.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States |
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| ID | Term |
|---|---|
| D015207 | Osteoarthritis, Hip |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| Pre-op, 1, 2, 3, 5 years after surgery |
| Assessment/Questionaire UCLA Activity Score | Measure of activity level | Pre-op, 1, 2, 3, 5 years after surgery |
| Assessment/Questionaire EQ-5D | General health and cost effectiveness measure | Pre-op, 1, 2, 3, 5 years after surgery |
| Assessment/Questionaire Case Mix indicator | Determines comorbidities | Pre-op, 1, 3, 5, 7, 10 years after surgery |
| D012216 |
| Rheumatic Diseases |