Aizthromycin or Clarithromycin in H-pylori Eradication Regimen

Comparison of Azithromycin or Clarithromycin in 3drugs Protocol of H-pylori Eradication Regimen

The Aim of this study is comparison between two regimens containing clarithromycinand azithromycin.

Eradication of helicobacter pylori is important for treatment of GU but ideal regimen is not available.

HP is resistant to metronidazole and clarithromycin, thus clarithromycin is expensive and it is not available in underdevelopment countries.

There are different articles about replacement clarithromycin with azithromycin as a method of eradication of HP that is decreases length of therapy and increases, effectiveness of drugs and decreases resistance of drugs.

The Aim of this study is comparison between two regimens containing clarithromycinand azithromycin.

Inclusion Criteria:

• patients with peptic ulcer due to H-pylori confirmed endoscopy and biopsy

Exclusion Criteria:

• patients who got H-pylori eradication treatment previously
• patients who used study drugs during 3months before study