Proof of Concept Study of BMS-823778 to Assess the Effects on Atherosclerosis

A Double-Blind, Placebo-Controlled, Randomized Study to Evaluate the Effects of BMS-823778 on Atherosclerotic Plaque Inflammation as Measured by Fluorodeoxyglucose (FDG)- Positron Emission Tomography (PET) in Patients With Atherosclerotic Cardiovascular Disease

The purpose of the study is to assess the effect of BMS-823778 on reducing atherosclerotic plaque inflammation

Inclusion Criteria:

• Documented atherosclerotic cardiovascular disease or at high risk of cardiovascular event
• On stable statin dose
• Clinically stable at time of screening and randomization

Exclusion Criteria:

• Women of child bearing potential
• Medical conditions that would impact the absorption of the study drug