ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes A... | NCT01663402

NCT01663402

ID	Type	Description	Link
2011-005698-21	EudraCT Number
U1111-1127-4323	Other Identifier	UTN

Status Module

Name	Class
Regeneron Pharmaceuticals	INDUSTRY

Oversight Module

Description Module

Design Module

Interventional Study Design

Biospecimen

No data available

No data is available for this block.

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Placebo	Placebo Comparator	Placebo (for alirocumab) subcutaneous (SC) injection every 2 weeks (Q2W) added to stable Lipid-Modifying Therapy (LMT) for up to 64 months.	Drug: Placebo Drug: LMT
Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Experimental	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when Low-Density Lipoprotein Cholesterol (LDL-C) levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).	Drug: Alirocumab Drug: LMT

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Alirocumab	Drug	Alirocumab administered as SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.	Alirocumab 75 mg Q2W/Up to 150 mg Q2W

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study	All MACE positively adjudicated by Clinical Events Committee (CEC) in a blinded fashion, were used in the analysis of the composite cardiovascular (CV) outcome measure comprised of Coronary Heart Disease (CHD) death, non-fatal Myocardial Infarction (MI), fatal and non-fatal ischemic stroke (IS), or unstable angina (UA) requiring hospitalization. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of MACE over time. Percentage of observed participants with outcome measure events during the study were reported.	From randomization up to 64 months

Secondary Outcomes

Measure	Description	Time Frame
Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study	All CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death, non-fatal non-fatal MI, UA requiring hospitalization, or ischemia-driven coronary revascularization procedure. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.

Other Outcomes

Measure	Description	Time Frame
Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis	Adjusted means and standard errors at Month 4, 12 and 48 from multiple imputation approach (to account for missing data) followed by analyses of covariance (ANCOVA) model with the fixed categorical effect of treatment group and the continuous fixed covariate of baseline LDL-C value, including all available post-baseline data from Month 1 up to Month 48 regardless of status on- or off-treatment.

Eligibility Module

Name	Affiliation	Role
Clinical Sciences & Operations	Sanofi	Study Director

Facility	Status	City	State	ZIP	Country	Contacts
Investigational Site Number 840163		Birmingham	Alabama	35235	United States
Investigational Site Number 840060

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
41321238	Derived	Tsimikas S, Szarek M, Cobbaert CM, Romijn F, Jukema JW, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Yuan C, Gong XM, Goodman SG, White HD, Witztum JL, Steg PG, Schwartz GG; ODYSSEY OUTCOMES Investigators. Oxidized Phospholipids, Lipoprotein(a), and Cardiovascular Outcomes After Acute Coronary Syndrome. Circulation. 2025 Dec 16;152(24):1666-1678. doi: 10.1161/CIRCULATIONAHA.125.073855. Epub 2025 Dec 1.
40995631

Results Section

Participant Flow Module

Arm/Group Information

ID	Title	Description
FG000	Placebo	Placebo (for alirocumab) SC injection every 2 weeks (Q2W) added to stable Lipid-Modifying Therapy (LMT) for up to 64 months.
FG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W

Baseline Characteristics Module

Outcome Measures Module

Adverse Events Module

More Info Module

Type	Includes Protocol	Includes SAP	Includes ICF	Document Label	Document Date	Document Uploaded Date	Document File Name
Prot	Yes	No	No	Study Protocol	Feb 25, 2016	Jan 21, 2019

Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Arm/Group Information

ID	Title	Description
BG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
BG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).
BG002	Total	Total of all reporting groups

Baseline Measures

Title

Description

Population Description

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Denominator Units Selected

Denominators

Classes

Age, Continuous

Mean

Standard Deviation

years

Title

Denominators

Categories

Title	Measurements
	OG00011.1 OG0019.5

Group IDs	Group Description	Statistical Method	Statistical Comment	P-Value	P-Value Comment	Parameter Type	Parameter Value	Dispersion Type	Dispersion Value	Confidence Interval Sides	Confidence Interval %	CI Lower Limit	CI Upper Limit	CI Lower Limit Comment	CI Upper Limit Comment	Estimate Comment	Tested Non-Inferiority	Non-Inferiority Type	Non-Inferiority Comment	Other Analysis Description
OG000 OG001	Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region (North America, South America, Western Europe, Eastern Europe, Asia, Rest of the world).	Log Rank		0.0003	Threshold for statistical significance at 0.0498 level.	Hazard Ratio (HR)	0.85			2-Sided	95	0.78	0.93					Superiority

Secondary

Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study

All CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death, non-fatal non-fatal MI, UA requiring hospitalization, or ischemia-driven coronary revascularization procedure. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study

All Major CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death and non-fatal MI. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any major CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study

All CV events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CV endpoint comprised of any non-fatal CHD event, any CV death and non-fatal IS. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CV event over time. Percentage of observed participants with outcome measure events during the study were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study

All-cause mortality, non-fatal MI and non-fatal IS positively adjudicated by CEC in a blinded fashion, were used in the analysis of this endpoint. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of all-cause mortality, non-fatal MI and non-fatal IS over time. Percentage of observed participants with outcome measure events during the study were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CHD death over time. Percentage of observed participants with CHD death (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CV death over time. Percentage of observed participants with CV death (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the all-cause death over time. Percentage of observed participants with all-cause death (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any non-fatal MI over time. Percentage of observed participants with any non-fatal MI (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of fatal or any non-fatal IS over time. Percentage of observed participants with fatal or any non-fatal IS (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any UA requiring hospitalization over time. Percentage of observed participants with any UA requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any ischemia-driven coronary revascularization procedure over time. Percentage of observed participants with any ischemia-driven coronary revascularization procedure (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Secondary

Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study

Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHF requiring hospitalization over time. Percentage of observed participants with any CHF requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.

ITT Population.

Posted

Number

percentage of participants

From randomization up to 64 months

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Other Pre-specified

Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis

Adjusted means and standard errors at Month 4, 12 and 48 from multiple imputation approach (to account for missing data) followed by analyses of covariance (ANCOVA) model with the fixed categorical effect of treatment group and the continuous fixed covariate of baseline LDL-C value, including all available post-baseline data from Month 1 up to Month 48 regardless of status on- or off-treatment.

ITT Population. Here, 'number analyzed' corresponds to the number of participants with the parameter measured and baseline measure available for each time-point. A multiple approach was used to account for participants with missing data.

Posted

Least Squares Mean

Standard Error

Percent change

Baseline, Months 4, 12 and 48

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Other Pre-specified

Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: On-Treatment Analysis

Adjusted Least-squares (LS) means and standard errors at Month 4, 12 and 48 were obtained from a mixed-effect model with repeated measures (MMRM) including available post-baseline on-treatment data from Month 1 up to Month 48 (i.e. up to 21 days after last injection).

Randomized and treated population. Here, 'number analyzed' signifies participants evaluable for this outcome measure at specified time points.

Posted

Least Squares Mean

Standard Error

Percent change

Baseline, Months 4, 12 and 48

ID	Title	Description
OG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.
OG001	Alirocumab 75 mg Q2W/Up to 150 mg Q2W	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).

Arm/Groups

ID	Title	Description	Deaths (Affected)	Deaths (At Risk)	Serious Events (Affected)	Serious Events (At Risk)	Other Events (Affected)	Other Events (At Risk)
EG000	Placebo	Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.	278	9,443	2,350	9,443	2,181	9,443
EG001	Alirocumab	Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).	238	9,451	2,202	9,451	2,203	9,451

Serious Adverse Events

Term	Organ System	Source Vocabulary	Assessment Type	Statistical Information
Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG00015 events15 affected9,443 at risk EG00111 events11 affected9,451 at risk
Anaemia Of Chronic Disease	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Anaemia Of Malignant Disease	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anaemia Vitamin B12 Deficiency	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Autoimmune Haemolytic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Coagulopathy	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Disseminated Intravascular Coagulation	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Febrile Neutropenia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Haemolytic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Haemorrhagic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG00018 events17 affected9,443 at risk EG00115 events14 affected9,451 at risk
Haemorrhagic Diathesis	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hypochromic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Iron Deficiency Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Leukocytosis	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Leukopenia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lymphadenitis	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lymphadenopathy	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Microcytic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nephrogenic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Normochromic Normocytic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Normocytic Anaemia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Thrombocytopenia	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG0012 events2 affected9,451 at risk
Thrombotic Thrombocytopenic Purpura	Blood and lymphatic system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Coronary Syndrome	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Left Ventricular Failure	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Myocardial Infarction	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0016 events6 affected9,451 at risk
Adams-Stokes Syndrome	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Angina Pectoris	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG000148 events133 affected9,443 at risk EG001136 events113 affected9,451 at risk
Angina Unstable	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG00110 events10 affected9,451 at risk
Aortic Valve Disease Mixed	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Aortic Valve Incompetence	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Aortic Valve Sclerosis	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Aortic Valve Stenosis	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00017 events17 affected9,443 at risk EG0017 events7 affected9,451 at risk
Arrhythmia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0015 events5 affected9,451 at risk
Arrhythmia Supraventricular	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Arteriosclerosis Coronary Artery	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Arteriospasm Coronary	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Atrial Fibrillation	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG000110 events98 affected9,443 at risk EG001103 events82 affected9,451 at risk
Atrial Flutter	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00014 events10 affected9,443 at risk EG00116 events14 affected9,451 at risk
Atrial Tachycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Atrioventricular Block	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Atrioventricular Block Complete	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0015 events5 affected9,451 at risk
Atrioventricular Block First Degree	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Atrioventricular Block Second Degree	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Bradycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG0018 events8 affected9,451 at risk
Bundle Branch Block Left	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bundle Branch Block Right	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cardiac Aneurysm	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Cardiac Arrest	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00010 events9 affected9,443 at risk EG0019 events9 affected9,451 at risk
Cardiac Discomfort	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cardiac Failure	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Cardiac Failure Acute	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0004 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Cardiac Failure Chronic	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cardiac Failure Congestive	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0014 events4 affected9,451 at risk
Cardiac Flutter	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cardiac Perforation	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cardiac Tamponade	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cardio-Respiratory Arrest	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events4 affected9,451 at risk
Cardiogenic Shock	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0014 events4 affected9,451 at risk
Cardiomyopathy	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0011 events1 affected9,451 at risk
Chordae Tendinae Rupture	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Conduction Disorder	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Congestive Cardiomyopathy	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Coronary Artery Disease	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00020 events20 affected9,443 at risk EG00126 events25 affected9,451 at risk
Coronary Artery Dissection	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Coronary Artery Occlusion	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Coronary Artery Stenosis	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0016 events6 affected9,451 at risk
Diastolic Dysfunction	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Extrasystoles	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intracardiac Mass	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intracardiac Thrombus	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Ischaemic Cardiomyopathy	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG0019 events9 affected9,451 at risk
Ischaemic Mitral Regurgitation	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Left Ventricular Dysfunction	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Low Cardiac Output Syndrome	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Microvascular Coronary Artery Disease	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mitral Valve Incompetence	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0019 events9 affected9,451 at risk
Mitral Valve Prolapse	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Myocardial Haemorrhage	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Myocardial Infarction	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Myocardial Ischaemia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00013 events13 affected9,443 at risk EG0014 events4 affected9,451 at risk
Myocardial Rupture	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Myocarditis	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Nodal Arrhythmia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Nodal Rhythm	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Palpitations	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0012 events2 affected9,451 at risk
Papillary Muscle Rupture	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pericardial Effusion	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Pericardial Haemorrhage	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pericarditis	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0016 events6 affected9,451 at risk
Pleuropericarditis	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Prinzmetal Angina	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pulseless Electrical Activity	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rhythm Idioventricular	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sinus Arrest	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Sinus Arrhythmia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sinus Bradycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Sinus Node Dysfunction	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG00113 events13 affected9,451 at risk
Sinus Tachycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Stress Cardiomyopathy	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Supraventricular Extrasystoles	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Supraventricular Tachycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00016 events12 affected9,443 at risk EG00111 events9 affected9,451 at risk
Systolic Dysfunction	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tachyarrhythmia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Tachycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Tricuspid Valve Disease	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ventricular Arrhythmia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Ventricular Extrasystoles	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0017 events7 affected9,451 at risk
Ventricular Fibrillation	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00017 events17 affected9,443 at risk EG0018 events8 affected9,451 at risk
Ventricular Hypokinesia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ventricular Tachycardia	Cardiac disorders	MedDra 20.1	Systematic Assessment	EG00033 events29 affected9,443 at risk EG00128 events24 affected9,451 at risk
Atrial Septal Defect	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bicuspid Aortic Valve	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bronchogenic Cyst	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dermoid Cyst	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Arteriovenous Malformation	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Haemorrhagic Arteriovenous Malformation	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hereditary Optic Atrophy	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Spinocerebellar Ataxia	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Thyroglossal Cyst	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Von Hippel-Lindau Disease	Congenital, familial and genetic disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Vestibular Syndrome	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Deafness Neurosensory	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypoacusis	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Sudden Hearing Loss	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tinnitus	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Tympanic Membrane Disorder	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Tympanic Membrane Perforation	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vertigo	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG00012 events12 affected9,443 at risk EG0019 events9 affected9,451 at risk
Vertigo Labyrinthine	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vertigo Positional	Ear and labyrinth disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events4 affected9,451 at risk
Adrenal Insufficiency	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Adrenocortical Insufficiency Acute	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Adrenocorticotropic Hormone Deficiency	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Autoimmune Hypothyroidism	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Basedow's Disease	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Goitre	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hyperthyroidism	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypothyroidism	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Inappropriate Antidiuretic Hormone Secretion	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pituitary Cyst	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Thyroid Mass	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Toxic Goitre	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Toxic Nodular Goitre	Endocrine disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Amaurosis Fugax	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Blepharochalasis	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cataract	Eye disorders	MedDra 20.1	Systematic Assessment	EG00013 events13 affected9,443 at risk EG00111 events11 affected9,451 at risk
Cataract Diabetic	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cataract Subcapsular	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Conjunctival Haemorrhage	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Corneal Degeneration	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diabetic Retinopathy	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Eye Muscle Entrapment	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Glaucoma	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Macular Degeneration	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ocular Myasthenia	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Optic Ischaemic Neuropathy	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Posterior Capsule Opacification	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Retinal Artery Embolism	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Retinal Artery Occlusion	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Retinal Detachment	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Retinal Haemorrhage	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Retinal Vein Occlusion	Eye disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ulcerative Keratitis	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Visual Acuity Reduced	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vitreous Detachment	Eye disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vitreous Haemorrhage	Eye disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Abdominal Adhesions	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Abdominal Discomfort	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Abdominal Distension	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Abdominal Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0014 events4 affected9,451 at risk
Abdominal Incarcerated Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Abdominal Pain	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00012 events12 affected9,443 at risk EG00110 events9 affected9,451 at risk
Abdominal Pain Upper	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0019 events9 affected9,451 at risk
Abdominal Strangulated Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Abdominal Wall Haematoma	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Alcoholic Pancreatitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events3 affected9,443 at risk EG0015 events5 affected9,451 at risk
Anal Fissure	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anal Fistula	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anal Incontinence	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anal Polyp	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Aphthous Ulcer	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Appendix Disorder	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ascites	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Barrett's Oesophagus	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Bile Acid Malabsorption	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Breath Odour	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Chronic Gastritis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Colitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0012 events2 affected9,451 at risk
Colitis Ischaemic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0011 events1 affected9,451 at risk
Colitis Microscopic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Colitis Ulcerative	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Constipation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Crohn's Disease	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dental Caries	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diabetic Gastroparesis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diarrhoea	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0014 events4 affected9,451 at risk
Diarrhoea Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dieulafoy's Vascular Malformation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diverticular Perforation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Diverticulum	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diverticulum Intestinal	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diverticulum Intestinal Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0018 events6 affected9,451 at risk
Duodenal Obstruction	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Duodenal Ulcer	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Duodenal Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00010 events9 affected9,443 at risk EG0014 events4 affected9,451 at risk
Duodenal Vascular Ectasia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Duodenitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Duodenitis Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dyspepsia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0017 events7 affected9,451 at risk
Dysphagia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Enteritis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Enterocolitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Enterocolitis Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Erosive Duodenitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Erosive Oesophagitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Faecaloma	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Femoral Hernia, Obstructive	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Fistula Of Small Intestine	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Food Poisoning	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Functional Gastrointestinal Disorder	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastric Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastric Polyps	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Gastric Ulcer	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events4 affected9,451 at risk
Gastric Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00012 events11 affected9,443 at risk EG00114 events14 affected9,451 at risk
Gastric Ulcer, Obstructive	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastritis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00019 events17 affected9,443 at risk EG00111 events11 affected9,451 at risk
Gastritis Erosive	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0017 events7 affected9,451 at risk
Gastritis Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastroduodenitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastroduodenitis Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Angiectasia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Angiodysplasia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastrointestinal Angiodysplasia Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastrointestinal Disorder	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Gastrointestinal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00013 events13 affected9,443 at risk EG00112 events11 affected9,451 at risk
Gastrointestinal Inflammation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Mucosal Disorder	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Pain	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Polyp Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastrointestinal Ulcer	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrooesophageal Reflux Disease	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00020 events19 affected9,443 at risk EG00124 events21 affected9,451 at risk
Gingival Bleeding	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Haematemesis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Haematochezia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0015 events5 affected9,451 at risk
Haemorrhagic Erosive Gastritis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Haemorrhoidal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0015 events5 affected9,451 at risk
Haemorrhoids	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0015 events5 affected9,451 at risk
Hiatus Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hiatus Hernia Strangulated	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ileal Perforation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ileus	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Ileus Paralytic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Incarcerated Hiatus Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Incarcerated Inguinal Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Incarcerated Umbilical Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Inguinal Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00015 events15 affected9,443 at risk EG00129 events29 affected9,451 at risk
Intestinal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intestinal Infarction	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intestinal Ischaemia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Intestinal Obstruction	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG0015 events5 affected9,451 at risk
Intestinal Perforation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Irritable Bowel Syndrome	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Large Intestinal Obstruction	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Large Intestinal Ulcer	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Large Intestine Perforation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events1 affected9,451 at risk
Large Intestine Polyp	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0014 events4 affected9,451 at risk
Lower Gastrointestinal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0013 events3 affected9,451 at risk
Lumbar Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mallory-Weiss Syndrome	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Megacolon	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Melaena	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mesenteric Artery Thrombosis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mesenteric Panniculitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nausea	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0015 events4 affected9,451 at risk
Obstruction Gastric	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Obstructive Pancreatitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0017 events5 affected9,451 at risk
Odynophagia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oedematous Pancreatitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Achalasia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Disorder	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Rupture	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Oesophageal Spasm	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Stenosis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Varices Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophagitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Oesophagitis Haemorrhagic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pancreatic Failure	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pancreatic Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pancreatic Pseudocyst	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pancreatitis	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0013 events3 affected9,451 at risk
Pancreatitis Acute	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG00016 events16 affected9,443 at risk EG00115 events15 affected9,451 at risk
Pancreatitis Chronic	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pancreatitis Necrotising	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Peptic Ulcer	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peptic Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Periodontal Disease	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Peritoneal Cyst	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Peritoneal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Rectal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Rectal Prolapse	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Rectal Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Retroperitoneal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Salivary Duct Obstruction	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Salivary Gland Calculus	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Small Intestinal Obstruction	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events4 affected9,443 at risk EG0017 events7 affected9,451 at risk
Small Intestinal Perforation	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Small Intestinal Ulcer Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Swollen Tongue	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tongue Haematoma	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Toothache	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Umbilical Hernia	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0017 events7 affected9,451 at risk
Umbilical Hernia, Obstructive	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Upper Gastrointestinal Haemorrhage	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0008 events7 affected9,443 at risk EG0016 events6 affected9,451 at risk
Varices Oesophageal	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vomiting	Gastrointestinal disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0015 events5 affected9,451 at risk
Asthenia	General disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0016 events6 affected9,451 at risk
Chest Discomfort	General disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0014 events4 affected9,451 at risk
Chest Pain	General disorders	MedDra 20.1	Systematic Assessment	EG00032 events29 affected9,443 at risk EG00127 events25 affected9,451 at risk
Death	General disorders	MedDra 20.1	Systematic Assessment	EG00033 events33 affected9,443 at risk EG00125 events25 affected9,451 at risk
Device Related Thrombosis	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Exercise Tolerance Decreased	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Facial Pain	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Fatigue	General disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gait Disturbance	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
General Physical Health Deterioration	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Granuloma	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Impaired Healing	General disorders	MedDra 20.1	Systematic Assessment	EG0004 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Implant Site Haematoma	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Implant Site Pain	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Incarcerated Hernia	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Influenza Like Illness	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Injection Site Reaction	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Malaise	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Medical Device Pain	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Medical Device Site Dermatitis	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Medical Device Site Joint Pain	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Medical Device Site Pain	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Multiple Organ Dysfunction Syndrome	General disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0015 events5 affected9,451 at risk
Non-Cardiac Chest Pain	General disorders	MedDra 20.1	Systematic Assessment	EG000256 events222 affected9,443 at risk EG001264 events219 affected9,451 at risk
Oedema Peripheral	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pacemaker Generated Arrhythmia	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pain	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pelvic Mass	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peripheral Swelling	General disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pyrexia	General disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0016 events6 affected9,451 at risk
Soft Tissue Inflammation	General disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Strangulated Hernia	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Sudden Cardiac Death	General disorders	MedDra 20.1	Systematic Assessment	EG00042 events42 affected9,443 at risk EG00136 events36 affected9,451 at risk
Sudden Death	General disorders	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG00114 events14 affected9,451 at risk
Systemic Inflammatory Response Syndrome	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vascular Stent Restenosis	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0019 events9 affected9,451 at risk
Vascular Stent Thrombosis	General disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vessel Puncture Site Haematoma	General disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vessel Puncture Site Haemorrhage	General disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Acute Hepatic Failure	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ampulla Of Vater Stenosis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bile Duct Stenosis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Bile Duct Stone	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0013 events3 affected9,451 at risk
Biliary Colic	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Biliary Dyskinesia	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Biliary Tract Disorder	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cholangitis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Cholangitis Acute	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cholangitis Sclerosing	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cholecystitis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG00014 events14 affected9,443 at risk EG0019 events8 affected9,451 at risk
Cholecystitis Acute	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG00014 events14 affected9,443 at risk EG00111 events11 affected9,451 at risk
Cholecystitis Chronic	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cholelithiasis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG00035 events35 affected9,443 at risk EG00125 events25 affected9,451 at risk
Cholestasis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Chronic Hepatitis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cirrhosis Alcoholic	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Drug-Induced Liver Injury	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG00115 events15 affected9,451 at risk
Gallbladder Disorder	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gallbladder Necrosis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gallbladder Perforation	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Cirrhosis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Congestion	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Failure	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Function Abnormal	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Haemorrhage	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Lesion	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Necrosis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Steatosis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Vein Dilatation	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatitis Acute	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatitis Alcoholic	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatitis Chronic Active	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatitis Toxic	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatocellular Injury	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hyperplastic Cholecystopathy	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ischaemic Hepatitis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events3 affected9,451 at risk
Jaundice Cholestatic	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Liver Disorder	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Liver Injury	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Steatohepatitis	Hepatobiliary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Allergy To Arthropod Bite	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Allergy To Arthropod Sting	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anaphylactic Reaction	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0014 events4 affected9,451 at risk
Anaphylactic Shock	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Contrast Media Allergy	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Drug Hypersensitivity	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hypersensitivity	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Iodine Allergy	Immune system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Abdominal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Abdominal Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Abdominal Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Abdominal Wall Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Abscess Limb	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Acute Endocarditis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Hepatitis C	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Anal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Appendiceal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Appendicitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00010 events10 affected9,443 at risk EG00113 events13 affected9,451 at risk
Appendicitis Perforated	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arthritis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Atypical Pneumonia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bacterial Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bacterial Prostatitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bacterial Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Biliary Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bone Tuberculosis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Borrelia Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Breast Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Breast Cellulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bronchiolitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bronchitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00021 events17 affected9,443 at risk EG00117 events16 affected9,451 at risk
Bronchitis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bronchitis Viral	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Brucellosis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bursitis Infective	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Campylobacter Gastroenteritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Candida Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cellulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00040 events37 affected9,443 at risk EG00135 events32 affected9,451 at risk
Cellulitis Of Male External Genital Organ	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cellulitis Staphylococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cholangitis Infective	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cholecystitis Infective	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0017 events7 affected9,451 at risk
Chronic Sinusitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Citrobacter Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Clostridium Difficile Colitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Cutaneous Tuberculosis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cystitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Cytomegalovirus Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dengue Fever	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0013 events3 affected9,451 at risk
Dermo-Hypodermitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Device Related Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diabetic Foot Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diabetic Gangrene	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diverticulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00011 events10 affected9,443 at risk EG0019 events9 affected9,451 at risk
Diverticulitis Intestinal Haemorrhagic	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Encephalitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Endocarditis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Enterobacter Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Enterococcal Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Enterococcal Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Enterocolitis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Enterocolitis Infectious	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Epididymitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Erysipelas	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0009 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Escherichia Pyelonephritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Escherichia Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Escherichia Urinary Tract Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0016 events6 affected9,451 at risk
External Ear Cellulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Extradural Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Gallbladder Empyema	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gangrene	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0014 events4 affected9,451 at risk
Gastric Ulcer Helicobacter	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastritis Viral	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastroenteritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00025 events25 affected9,443 at risk EG00131 events26 affected9,451 at risk
Gastroenteritis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastroenteritis Salmonella	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastroenteritis Viral	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Graft Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Groin Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Haemophilus Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hantaviral Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Helicobacter Gastritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Amoebiasis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hepatic Infection Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatitis C	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Herpes Virus Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Herpes Zoster	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0014 events4 affected9,451 at risk
Iatrogenic Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Implant Site Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Infected Bite	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Infected Cyst	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Infected Skin Ulcer	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Infectious Colitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0010 events0 affected9,451 at risk
Infectious Pleural Effusion	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Infective Exacerbation Of Chronic Obstructive Airways Disease	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0009 events7 affected9,443 at risk EG00112 events11 affected9,451 at risk
Influenza	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0015 events5 affected9,451 at risk
Injection Site Cellulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Klebsiella Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Labyrinthitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Laryngitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Latent Tuberculosis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Liver Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Localised Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lower Respiratory Tract Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00010 events10 affected9,443 at risk EG00112 events11 affected9,451 at risk
Ludwig Angina	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0016 events5 affected9,451 at risk
Lyme Disease	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mastitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mastoiditis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mediastinitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Medical Device Site Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Meningitis Aseptic	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Meningoencephalitis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Necrotising Fasciitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Neutropenic Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ophthalmic Herpes Zoster	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Oral Herpes	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Orchitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Osteomyelitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00013 events8 affected9,443 at risk EG0016 events5 affected9,451 at risk
Osteomyelitis Acute	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Osteomyelitis Chronic	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Otitis Externa	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Otitis Media	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Otitis Media Acute	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pancreas Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pelvic Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pelvic Inflammatory Disease	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Perichondritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Perihepatic Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Perineal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Periodontitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Periorbital Cellulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Perirectal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peritoneal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peritonitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0015 events5 affected9,451 at risk
Peritonsillar Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pharyngitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pharyngolaryngeal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pilonidal Cyst	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pleurisy Viral	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pneumonia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG000123 events108 affected9,443 at risk EG00198 events96 affected9,451 at risk
Pneumonia Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0015 events5 affected9,451 at risk
Pneumonia Chlamydial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pneumonia Escherichia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pneumonia Haemophilus	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pneumonia Influenzal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pneumonia Klebsiella	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pneumonia Legionella	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Pneumonia Mycoplasmal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pneumonia Pneumococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pneumonia Staphylococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pneumonia Streptococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pneumonia Viral	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Post Procedural Cellulitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Post Procedural Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Post Procedural Pneumonia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Post Procedural Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Post Viral Fatigue Syndrome	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Postoperative Wound Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00014 events13 affected9,443 at risk EG00113 events13 affected9,451 at risk
Proctitis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pseudomembranous Colitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pseudomonal Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pseudomonal Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Psoas Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pulmonary Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Pulmonary Tuberculosis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0013 events3 affected9,451 at risk
Pyelonephritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG0014 events4 affected9,451 at risk
Pyelonephritis Acute	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0016 events6 affected9,451 at risk
Pyelonephritis Chronic	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events1 affected9,451 at risk
Renal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Respiratory Syncytial Virus Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Respiratory Tract Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Scrotal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Scrub Typhus	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00038 events35 affected9,443 at risk EG00120 events20 affected9,451 at risk
Septic Shock	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00013 events12 affected9,443 at risk EG00111 events11 affected9,451 at risk
Sinusitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sinusitis Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Staphylococcal Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Staphylococcal Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Staphylococcal Osteomyelitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Staphylococcal Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Streptococcal Bacteraemia	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Streptococcal Endocarditis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Streptococcal Sepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Subcutaneous Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0016 events6 affected9,451 at risk
Systemic Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tonsillitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tooth Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0010 events0 affected9,451 at risk
Toxic Shock Syndrome	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tracheitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Tracheobronchitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tuberculosis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Tuberculous Pleurisy	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Upper Respiratory Tract Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG0017 events7 affected9,451 at risk
Urethritis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Tract Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00035 events33 affected9,443 at risk EG00128 events27 affected9,451 at risk
Urinary Tract Infection Bacterial	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Tract Infection Enterococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Tract Infection Staphylococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urosepsis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG00011 events10 affected9,443 at risk EG00116 events16 affected9,451 at risk
Vestibular Neuronitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Viral Cardiomyopathy	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Viral Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0018 events8 affected9,451 at risk
Viral Labyrinthitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Viral Myocarditis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Viral Pericarditis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Viral Upper Respiratory Tract Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Visceral Leishmaniasis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vulval Abscess	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vulvovaginal Candidiasis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Wound Infection	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0010 events0 affected9,451 at risk
Wound Infection Staphylococcal	Infections and infestations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Abdominal Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Abdominal Wound Dehiscence	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Accidental Overdose	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG00014 events9 affected9,443 at risk EG0018 events8 affected9,451 at risk
Acetabulum Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Alcohol Poisoning	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Allergic Transfusion Reaction	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anaemia Postoperative	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Anaesthetic Complication Neurological	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Anastomotic Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ankle Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0009 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Aortic Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Arterial Bypass Thrombosis	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arterial Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Arthropod Bite	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arthropod Sting	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Auricular Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Blast Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bone Contusion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Brachial Plexus Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Brain Contusion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Brain Herniation	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Carbon Monoxide Poisoning	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cardiac Contusion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cardiac Valve Replacement Complication	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cervical Vertebral Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Chemical Burn Of Gastrointestinal Tract	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Chest Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Clavicle Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0011 events1 affected9,451 at risk
Concussion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0012 events2 affected9,451 at risk
Confusion Postoperative	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Contusion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0006 events4 affected9,443 at risk EG0013 events3 affected9,451 at risk
Coronary Artery Restenosis	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0011 events1 affected9,451 at risk
Craniocerebral Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Delayed Recovery From Anaesthesia	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Electric Shock	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Extra-Axial Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Extradural Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Eye Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Face Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Facial Bones Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Fall	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG00034 events32 affected9,443 at risk EG00126 events26 affected9,451 at risk
Femoral Neck Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0016 events6 affected9,451 at risk
Femur Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG00114 events13 affected9,451 at risk
Fibula Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0010 events0 affected9,451 at risk
Foot Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Forearm Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Foreign Body In Urogenital Tract	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Fracture Displacement	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Fractured Skull Depressed	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Stoma Necrosis	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gun Shot Wound	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hand Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0015 events5 affected9,451 at risk
Head Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Heat Stroke	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hip Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0018 events7 affected9,451 at risk
Humerus Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Hyphaema	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Incision Site Pain	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Incisional Hernia	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intentional Overdose	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG00018 events8 affected9,443 at risk EG0016 events6 affected9,451 at risk
Jaw Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Joint Dislocation	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Joint Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Laceration	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ligament Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ligament Rupture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ligament Sprain	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Limb Crushing Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Limb Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0012 events2 affected9,451 at risk
Limb Traumatic Amputation	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lip Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lower Limb Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Lumbar Vertebral Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0016 events6 affected9,451 at risk
Mallet Finger	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Meniscus Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events3 affected9,443 at risk EG0017 events6 affected9,451 at risk
Multiple Fractures	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0014 events4 affected9,451 at risk
Multiple Injuries	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Muscle Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Muscle Rupture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Muscle Strain	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Nerve Root Injury Lumbar	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Oesophageal Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pelvic Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Penetrating Abdominal Trauma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Periorbital Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peripheral Artery Restenosis	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Periprosthetic Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Perirenal Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pneumothorax Traumatic	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Post Concussion Syndrome	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Post Laminectomy Syndrome	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Post Procedural Bile Leak	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Post Procedural Fistula	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events2 affected9,451 at risk
Post Procedural Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Post Procedural Haematuria	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Post Procedural Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Post Procedural Inflammation	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Post Procedural Pulmonary Embolism	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Post Procedural Swelling	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Post-Traumatic Pain	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Postoperative Ileus	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Postoperative Renal Failure	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Postoperative Respiratory Failure	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Postoperative Thoracic Procedure Complication	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Postoperative Thrombosis	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Postpericardiotomy Syndrome	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Procedural Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Procedural Hypertension	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Procedural Hypotension	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Procedural Intestinal Perforation	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Procedural Pain	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0014 events4 affected9,451 at risk
Procedural Pneumothorax	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Pubis Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pulmonary Contusion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Radiation Associated Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Radiation Skin Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Radius Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0016 events6 affected9,451 at risk
Rib Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0016 events6 affected9,451 at risk
Road Traffic Accident	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG00019 events19 affected9,443 at risk EG00114 events14 affected9,451 at risk
Scapula Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Scrotal Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Seroma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Silicosis	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events1 affected9,451 at risk
Skin Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Skull Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Soft Tissue Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Spinal Compression Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Spinal Cord Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Spinal Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Splenic Rupture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Stab Wound	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Sternal Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Stoma Site Discharge	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Stomal Hernia	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Subarachnoid Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0011 events1 affected9,451 at risk
Subdural Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Tendon Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tendon Rupture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0016 events6 affected9,451 at risk
Thermal Burn	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Thoracic Vertebral Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tibia Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0012 events2 affected9,451 at risk
Tooth Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Toxicity To Various Agents	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Tracheostomy Malfunction	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Traumatic Haematoma	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Traumatic Haemothorax	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events4 affected9,451 at risk
Traumatic Intracranial Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Traumatic Liver Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Traumatic Renal Injury	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Traumatic Ulcer	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ulna Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Upper Limb Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Urinary Retention Postoperative	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vascular Access Site Haemorrhage	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vascular Access Site Pseudoaneurysm	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vascular Graft Occlusion	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vascular Pseudoaneurysm	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vascular Pseudoaneurysm Ruptured	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Wound	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Wound Dehiscence	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Wrist Fracture	Injury, poisoning and procedural complications	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Alanine Aminotransferase Increased	Investigations	MedDra 20.1	Systematic Assessment	EG00011 events11 affected9,443 at risk EG00110 events10 affected9,451 at risk
Anticoagulation Drug Level Above Therapeutic	Investigations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Blood Calcium Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Blood Creatine Phosphokinase Mb Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Blood Creatine Phosphokinase Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0015 events5 affected9,451 at risk
Blood Creatinine Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Blood Potassium Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Blood Pressure Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Brain Natriuretic Peptide Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
C-Reactive Protein Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cardiac Stress Test Abnormal	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ejection Fraction Decreased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Electrocardiogram Qt Prolonged	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Exercise Electrocardiogram Abnormal	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Glomerular Filtration Rate Decreased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hiv Test Positive	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Haematocrit Decreased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Haematocrit Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Haemoglobin Decreased	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Enzyme Abnormal	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hepatic Enzyme Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0015 events5 affected9,451 at risk
Hepatitis C Virus Test Positive	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Human Papilloma Virus Test Positive	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Influenza A Virus Test Positive	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
International Normalised Ratio Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Liver Function Test Abnormal	Investigations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Liver Function Test Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Mycobacterium Tuberculosis Complex Test Positive	Investigations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Scan Myocardial Perfusion	Investigations	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Transaminases Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0015 events5 affected9,451 at risk
Troponin Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tumour Marker Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Weight Decreased	Investigations	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
White Blood Cell Count Increased	Investigations	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Dehydration	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG00013 events13 affected9,443 at risk EG00114 events13 affected9,451 at risk
Diabetes Mellitus	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events4 affected9,451 at risk
Diabetes Mellitus Inadequate Control	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG00021 events16 affected9,443 at risk EG00120 events20 affected9,451 at risk
Diabetic Complication	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diabetic Ketoacidosis	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG00013 events9 affected9,443 at risk EG0014 events4 affected9,451 at risk
Diabetic Ketosis	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diabetic Metabolic Decompensation	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Electrolyte Imbalance	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Fluid Overload	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Fluid Retention	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gout	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hyperammonaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypercalcaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hyperglycaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG00112 events10 affected9,451 at risk
Hyperglycaemic Hyperosmolar Nonketotic Syndrome	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hyperinsulinaemic Hypoglycaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0014 events3 affected9,451 at risk
Hyperkalaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0014 events4 affected9,451 at risk
Hypernatraemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypertriglyceridaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hyperuricaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypervolaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypoalbuminaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypocalcaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypoglycaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0017 events6 affected9,451 at risk
Hypokalaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG00012 events10 affected9,443 at risk EG00113 events8 affected9,451 at risk
Hypomagnesaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hyponatraemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0009 events8 affected9,443 at risk EG0013 events3 affected9,451 at risk
Hypovolaemia	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lactic Acidosis	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metabolic Acidosis	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0015 events5 affected9,451 at risk
Metabolic Disorder	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metabolic Syndrome	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Obesity	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0013 events3 affected9,451 at risk
Type 1 Diabetes Mellitus	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events1 affected9,451 at risk
Type 2 Diabetes Mellitus	Metabolism and nutrition disorders	MedDra 20.1	Systematic Assessment	EG00036 events36 affected9,443 at risk EG00137 events37 affected9,451 at risk
Ankylosing Spondylitis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arthralgia	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Arthritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0015 events5 affected9,451 at risk
Arthrofibrosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Back Pain	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG00011 events10 affected9,443 at risk EG00110 events9 affected9,451 at risk
Bone Cyst	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bursitis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Cervical Spinal Stenosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Chondropathy	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Compartment Syndrome	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Costochondritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0013 events3 affected9,451 at risk
Dupuytren's Contracture	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Enthesopathy	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Femoroacetabular Impingement	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Foot Deformity	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gouty Arthritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intervertebral Disc Degeneration	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Intervertebral Disc Disorder	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Intervertebral Disc Protrusion	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG00022 events21 affected9,443 at risk EG00121 events21 affected9,451 at risk
Joint Effusion	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Joint Instability	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Joint Range Of Motion Decreased	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lumbar Spinal Stenosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG00110 events10 affected9,451 at risk
Meniscal Degeneration	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Mobility Decreased	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Muscle Necrosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Muscle Spasms	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0004 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Muscle Tightness	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Muscular Weakness	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Musculoskeletal Chest Pain	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG00044 events35 affected9,443 at risk EG00126 events24 affected9,451 at risk
Musculoskeletal Pain	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0005 events4 affected9,443 at risk EG0015 events5 affected9,451 at risk
Myalgia	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0015 events5 affected9,451 at risk
Myopathy	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Myositis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Neck Pain	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Neuropathic Arthropathy	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Osteitis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Osteoarthritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG00051 events46 affected9,443 at risk EG00154 events50 affected9,451 at risk
Osteochondrosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0010 events0 affected9,451 at risk
Osteopenia	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Osteoporotic Fracture	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pain In Extremity	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0015 events5 affected9,451 at risk
Pathological Fracture	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Periarthritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Polymyalgia Rheumatica	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pseudarthrosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Psoriatic Arthropathy	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rhabdomyolysis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0013 events3 affected9,451 at risk
Rheumatic Fever	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rheumatoid Arthritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0013 events3 affected9,451 at risk
Rotator Cuff Syndrome	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG00110 events9 affected9,451 at risk
Spinal Column Stenosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0014 events4 affected9,451 at risk
Spinal Disorder	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Spinal Ligament Ossification	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Spinal Osteoarthritis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0019 events9 affected9,451 at risk
Spinal Pain	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Spondylolisthesis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Sympathetic Posterior Cervical Syndrome	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Synovial Cyst	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Synovitis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Systemic Lupus Erythematosus	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Tendonitis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Vertebral Foraminal Stenosis	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Lymphocytic Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Acute Myeloid Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Adenocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Adenocarcinoma Gastric	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Adenocarcinoma Of Colon	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG00014 events14 affected9,443 at risk EG00110 events10 affected9,451 at risk
Adrenal Adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Adrenal Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anal Cancer Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Anal Squamous Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anaplastic Large Cell Lymphoma T- And Null-Cell Types	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
B-Cell Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
B-Cell Small Lymphocytic Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Basal Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG00018 events14 affected9,443 at risk EG00112 events11 affected9,451 at risk
Benign Ovarian Tumour	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Benign Salivary Gland Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bladder Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Bladder Cancer Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bladder Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Bladder Papilloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bladder Transitional Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0009 events9 affected9,443 at risk EG0018 events8 affected9,451 at risk
Bladder Transitional Cell Carcinoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bladder Transitional Cell Carcinoma Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bowen's Disease	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Brain Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Brain Neoplasm Benign	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Breast Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Breast Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Breast Cancer Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Breast Cancer Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Breast Cancer Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bronchial Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cancer Pain	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Carcinoid Tumour Of The Appendix	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Carcinoid Tumour Pulmonary	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Cardiac Myxoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cardiac Valve Fibroelastoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cerebellar Tumour	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cervix Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cervix Carcinoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cholesteatoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Chronic Lymphocytic Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Chronic Myeloid Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Chronic Myelomonocytic Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Clear Cell Renal Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Colon Adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0016 events6 affected9,451 at risk
Colon Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Colon Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Colon Cancer Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Colon Cancer Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Colorectal Adenocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Colorectal Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Colorectal Cancer Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Craniopharyngioma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diffuse Large B-Cell Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Ductal Adenocarcinoma Of Pancreas	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Endometrial Adenocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastric Cancer Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Gastrointestinal Stromal Tumour	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrointestinal Tract Adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Gastrooesophageal Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Glioblastoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Glioblastoma Multiforme	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Haemangioma Of Bone	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hair Follicle Tumour Benign	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hepatic Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hepatocellular Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hodgkin's Disease	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hodgkin's Disease Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypopharyngeal Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Inflammatory Pseudotumour	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intraductal Proliferative Breast Lesion	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Invasive Ductal Breast Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0018 events8 affected9,451 at risk
Invasive Lobular Breast Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Large Cell Lung Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Large Cell Lung Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Laryngeal Cancer Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Laryngeal Squamous Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Lentigo Maligna	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lip Squamous Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lipoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lung Adenocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0015 events5 affected9,451 at risk
Lung Adenocarcinoma Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Lung Adenocarcinoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lung Adenocarcinoma Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Lung Adenocarcinoma Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Lung Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Carcinoma Cell Type Unspecified Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Carcinoma Cell Type Unspecified Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Carcinoma Cell Type Unspecified Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Lung Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Lung Neoplasm Malignant	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0014 events4 affected9,451 at risk
Lung Squamous Cell Carcinoma Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Squamous Cell Carcinoma Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Lung Squamous Cell Carcinoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Squamous Cell Carcinoma Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Lung Squamous Cell Carcinoma Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Malignant Anorectal Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Malignant Ascites	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Malignant Glioma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Malignant Melanoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Malignant Melanoma In Situ	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Malignant Melanoma Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Malignant Melanoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Malignant Melanoma Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Malignant Palate Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Malignant Pleural Effusion	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Malignant Sweat Gland Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Meningioma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Metastases To Bone	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Metastases To Central Nervous System	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastases To Liver	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Metastases To Lung	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0012 events2 affected9,451 at risk
Metastases To Lymph Nodes	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Metastases To Peritoneum	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastases To Spine	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastatic Bronchial Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastatic Carcinoma Of The Bladder	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Metastatic Gastric Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastatic Malignant Melanoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastatic Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Metastatic Renal Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Metastatic Squamous Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Monoclonal Gammopathy	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Mucinous Cystadenocarcinoma Ovary	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Myelodysplastic Syndrome	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Myeloproliferative Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nasal Cavity Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Neuroendocrine Carcinoma Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Neuroendocrine Tumour	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Neuroendocrine Tumour Of The Lung	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Neuroendocrine Tumour Of The Lung Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Non-Hodgkin's Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Non-Hodgkin's Lymphoma Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Non-Hodgkin's Lymphoma Recurrent	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Non-Small Cell Lung Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Non-Small Cell Lung Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Non-Small Cell Lung Cancer Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Non-Small Cell Lung Cancer Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Oesophageal Adenocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Oesophageal Adenocarcinoma Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oesophageal Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oropharyngeal Cancer Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Oropharyngeal Squamous Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Ovarian Adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pancreatic Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pancreatic Carcinoma Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pancreatic Carcinoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pancreatic Carcinoma Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pancreatic Neuroendocrine Tumour	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Papillary Thyroid Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Parathyroid Tumour Benign	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Penile Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peritoneal Mesothelioma Malignant	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Phaeochromocytoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pituitary Tumour Benign	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Plasma Cell Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Plasma Cell Myeloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Plasmacytoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pleural Mesothelioma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Polycythaemia Vera	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Prostate Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG00017 events17 affected9,443 at risk EG00118 events18 affected9,451 at risk
Prostate Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Prostate Cancer Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0016 events6 affected9,451 at risk
Prostate Cancer Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0017 events7 affected9,451 at risk
Prostate Cancer Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0011 events1 affected9,451 at risk
Prostate Cancer Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Prostatic Adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rectal Adenocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0012 events2 affected9,451 at risk
Rectal Adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rectal Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Rectal Cancer Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rectal Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Rectosigmoid Cancer Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Cancer Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Cell Carcinoma Stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Renal Cell Carcinoma Stage Ii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Cell Carcinoma Stage Iii	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Renal Oncocytoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Salivary Gland Cancer Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Schwannoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Seborrhoeic Keratosis	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sinonasal Papilloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sinus Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Skin Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Skin Papilloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Small Cell Lung Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Small Cell Lung Cancer Limited Stage	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Small Cell Lung Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Squamous Cell Carcinoma Of Lung	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Squamous Cell Carcinoma Of Skin	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG0012 events2 affected9,451 at risk
Squamous Cell Carcinoma Of The Cervix	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Squamous Cell Carcinoma Of The Hypopharynx	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Squamous Cell Carcinoma Of The Tongue	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Squamous Cell Carcinoma Of The Vulva	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Synovial Sarcoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tongue Carcinoma Stage Iv	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tonsil Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Transitional Cell Cancer Of Renal Pelvis And Ureter Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Transitional Cell Carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0012 events2 affected9,451 at risk
Tumour Haemorrhage	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Bladder Sarcoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Uterine Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Uterine Leiomyoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vocal Cord Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Vulval Cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vulval Cancer Metastatic	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Alcoholic Seizure	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Amnesia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0014 events4 affected9,451 at risk
Amyotrophic Lateral Sclerosis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Aphasia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ataxia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Autonomic Nervous System Imbalance	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Axonal Neuropathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Balance Disorder	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Brain Injury	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Brain Oedema	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Carotid Arteriosclerosis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Carotid Artery Disease	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Carotid Artery Occlusion	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Carotid Artery Stenosis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG00019 events19 affected9,443 at risk EG00114 events14 affected9,451 at risk
Carotid Artery Thrombosis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Carotid Sinus Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Carpal Tunnel Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0016 events6 affected9,451 at risk
Cauda Equina Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cerebral Atrophy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cerebral Disorder	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cerebral Haemorrhage	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cerebral Ischaemia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cerebrospinal Fistula	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cerebrovascular Accident	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cervical Radiculopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Chronic Inflammatory Demyelinating Polyradiculoneuropathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cognitive Disorder	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Coma	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Coordination Abnormal	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Cubital Tunnel Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dementia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0014 events4 affected9,451 at risk
Dementia Alzheimer's Type	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Demyelinating Polyneuropathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Depressed Level Of Consciousness	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diabetic Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diabetic Neuropathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Dizziness	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Dizziness Exertional	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dysarthria	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0017 events5 affected9,451 at risk
Epilepsy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG0015 events5 affected9,451 at risk
Epileptic Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Essential Tremor	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Extrapyramidal Disorder	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Facial Paralysis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Focal Dyscognitive Seizures	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Generalised Tonic-Clonic Seizure	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Haemorrhage Intracranial	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Haemorrhagic Stroke	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Headache	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0008 events7 affected9,443 at risk EG0014 events4 affected9,451 at risk
Hemianopia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hemiparesis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hemiplegia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hyperaesthesia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hyperglycaemic Seizure	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hypoaesthesia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hypoglycaemic Seizure	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hyponatraemic Seizure	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hypoxic-Ischaemic Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intercostal Neuralgia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intracranial Aneurysm	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intracranial Mass	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intracranial Venous Sinus Thrombosis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intraventricular Haemorrhage	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ischaemic Stroke	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Limbic Encephalitis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Loss Of Consciousness	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0018 events6 affected9,451 at risk
Lumbar Radiculopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Lumbosacral Radiculopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Memory Impairment	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Metabolic Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0017 events7 affected9,451 at risk
Migraine	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Migraine With Aura	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Mixed Dementia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Monoparesis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Multiple Sclerosis Relapse	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0003 events2 affected9,443 at risk EG0012 events1 affected9,451 at risk
Myelopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Myoclonus	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Nerve Compression	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Neuralgia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Neuromuscular Pain	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Neuropathy Peripheral	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0010 events0 affected9,451 at risk
Occipital Neuralgia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Paraesthesia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0011 events1 affected9,451 at risk
Paralysis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Parkinson's Disease	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Parkinsonism	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Partial Seizures With Secondary Generalisation	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peripheral Nerve Lesion	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Peripheral Sensory Neuropathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Petit Mal Epilepsy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Polyneuropathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Posterior Reversible Encephalopathy Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Postictal Paralysis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Presyncope	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0019 events9 affected9,451 at risk
Pyramidal Tract Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Radial Nerve Palsy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Radicular Pain	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Radiculopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events2 affected9,451 at risk
Ruptured Cerebral Aneurysm	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Sciatica	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0016 events6 affected9,451 at risk
Seizure	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0007 events7 affected9,443 at risk EG0015 events5 affected9,451 at risk
Sensory Loss	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Spinal Cord Compression	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Spondylitic Myelopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Status Epilepticus	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Syncope	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG00082 events73 affected9,443 at risk EG00173 events67 affected9,451 at risk
Toxic Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Transient Global Amnesia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Transient Ischaemic Attack	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0014 events4 affected9,451 at risk
Tremor	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Trigeminal Neuralgia	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ulnar Neuritis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ulnar Tunnel Syndrome	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vith Nerve Paralysis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vith Nerve Paresis	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vascular Encephalopathy	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vertebral Artery Occlusion	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vertebrobasilar Insufficiency	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vertigo Cns Origin	Nervous system disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Device Dislocation	Product Issues	MedDra 20.1	Systematic Assessment	EG0003 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Device Lead Damage	Product Issues	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Device Malfunction	Product Issues	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Device Occlusion	Product Issues	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lead Dislodgement	Product Issues	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Thrombosis In Device	Product Issues	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events1 affected9,451 at risk
Acute Psychosis	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Adjustment Disorder With Mixed Disturbance Of Emotion And Conduct	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Affective Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Agoraphobia	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Alcohol Abuse	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0016 events6 affected9,451 at risk
Alcoholic Psychosis	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Alcoholism	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Anger	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Anxiety	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0009 events5 affected9,443 at risk EG0013 events3 affected9,451 at risk
Anxiety Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bipolar I Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bipolar Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Borderline Personality Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bradyphrenia	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Catatonia	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Completed Suicide	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0013 events3 affected9,451 at risk
Confusional State	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Conversion Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Delirium	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Delirium Tremens	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Delusional Disorder, Unspecified Type	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Depression	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG00026 events25 affected9,443 at risk EG00118 events13 affected9,451 at risk
Depression Suicidal	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Drug Abuse	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Factitious Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hallucination	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Homicidal Ideation	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Insomnia	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Major Depression	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0015 events5 affected9,451 at risk
Mental Status Changes	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG00110 events7 affected9,451 at risk
Mood Disorder Due To A General Medical Condition	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Panic Attack	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Post-Traumatic Stress Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Sleep Disorder	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Suicidal Behaviour	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Suicidal Ideation	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG00010 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Suicide Attempt	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG00015 events14 affected9,443 at risk EG0015 events5 affected9,451 at risk
Transient Psychosis	Psychiatric disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Acute Kidney Injury	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG00074 events62 affected9,443 at risk EG00159 events57 affected9,451 at risk
Acute Prerenal Failure	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Bladder Dilatation	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bladder Outlet Obstruction	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bladder Perforation	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bladder Tamponade	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Calculus Bladder	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Calculus Urinary	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Chronic Kidney Disease	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG00016 events15 affected9,443 at risk EG00114 events13 affected9,451 at risk
Cystitis Glandularis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cystitis Interstitial	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Cystitis Noninfective	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diabetic Cystopathy	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diabetic Nephropathy	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
End Stage Renal Disease	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Glomerulonephritis Proliferative	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Glomerulonephropathy	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Haematuria	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG00015 events13 affected9,443 at risk EG0019 events9 affected9,451 at risk
Hydronephrosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG0012 events2 affected9,451 at risk
Hypertensive Nephropathy	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Iga Nephropathy	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lower Urinary Tract Symptoms	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nephrolithiasis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG00021 events21 affected9,443 at risk EG00115 events15 affected9,451 at risk
Nephropathy	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nephropathy Toxic	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG00110 events10 affected9,451 at risk
Nephrosclerosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nephrotic Syndrome	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pelvi-Ureteric Obstruction	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Postrenal Failure	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Artery Occlusion	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Artery Stenosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Colic	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0014 events4 affected9,451 at risk
Renal Cyst	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Cyst Haemorrhage	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Disorder	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Failure	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0018 events8 affected9,451 at risk
Renal Haematoma	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Impairment	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0004 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Infarct	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Renal Mass	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Pain	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Tubular Disorder	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renal Tubular Necrosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Renal Vein Thrombosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Stress Urinary Incontinence	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Tubulointerstitial Nephritis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ureteral Disorder	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ureteric Stenosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Ureterolithiasis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG00015 events15 affected9,443 at risk EG00114 events12 affected9,451 at risk
Urethral Stenosis	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0015 events4 affected9,451 at risk
Urinary Bladder Haemorrhage	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Bladder Rupture	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Incontinence	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinary Retention	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Urinary Tract Obstruction	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urinoma	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urogenital Fistula	Renal and urinary disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Acquired Hydrocele	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0012 events2 affected9,451 at risk
Acquired Phimosis	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Benign Prostatic Hyperplasia	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG00013 events13 affected9,443 at risk EG00116 events16 affected9,451 at risk
Breast Mass	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Breast Pain	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dysfunctional Uterine Bleeding	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Endometrial Hyperplasia	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Erectile Dysfunction	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Menorrhagia	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Metrorrhagia	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Ovarian Cyst	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peyronie's Disease	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Prostatitis	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Rectocele	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Scrotal Ulcer	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Spermatocele	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Testicular Cyst	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Uterine Haemorrhage	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Uterine Polyp	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Uterine Prolapse	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Uterovaginal Prolapse	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vaginal Dysplasia	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vaginal Haemorrhage	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vaginal Prolapse	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Varicocele	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Vulva Cyst	Reproductive system and breast disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acquired Diaphragmatic Eventration	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Acute Pulmonary Oedema	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00010 events10 affected9,443 at risk EG0016 events6 affected9,451 at risk
Acute Respiratory Distress Syndrome	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Acute Respiratory Failure	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00035 events24 affected9,443 at risk EG00121 events19 affected9,451 at risk
Adenoidal Hypertrophy	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Aspiration	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Asthma	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG00110 events10 affected9,451 at risk
Atelectasis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bronchial Hyperreactivity	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bronchiectasis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Bronchitis Chronic	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Bronchospasm	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Choking	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Chronic Obstructive Pulmonary Disease	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00076 events51 affected9,443 at risk EG00147 events38 affected9,451 at risk
Chronic Respiratory Failure	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Cough	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dyspnoea	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00012 events12 affected9,443 at risk EG00121 events20 affected9,451 at risk
Dyspnoea Exertional	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Emphysema	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Epistaxis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00012 events12 affected9,443 at risk EG00110 events10 affected9,451 at risk
Haemoptysis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Haemothorax	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Hyperventilation	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hypoventilation	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hypoxia	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Idiopathic Pulmonary Fibrosis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Interstitial Lung Disease	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Laryngeal Haemorrhage	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Laryngeal Oedema	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Laryngospasm	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lung Disorder	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lung Infiltration	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nasal Mucosal Ulcer	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nasal Obstruction	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nasal Polyps	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Nasal Septum Deviation	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Nasal Turbinate Hypertrophy	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pleural Effusion	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0019 events7 affected9,451 at risk
Pleurisy	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pleuritic Pain	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0014 events4 affected9,451 at risk
Pneumonia Aspiration	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0008 events8 affected9,443 at risk EG0017 events7 affected9,451 at risk
Pneumothorax	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pulmonary Alveolar Haemorrhage	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pulmonary Calcification	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pulmonary Congestion	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pulmonary Embolism	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00019 events19 affected9,443 at risk EG00116 events16 affected9,451 at risk
Pulmonary Fibrosis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0012 events2 affected9,451 at risk
Pulmonary Hypertension	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pulmonary Infarction	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pulmonary Mass	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Pulmonary Oedema	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0005 events5 affected9,443 at risk EG0012 events2 affected9,451 at risk
Respiratory Acidosis	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Respiratory Arrest	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Respiratory Disorder	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Respiratory Distress	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Respiratory Failure	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG00016 events15 affected9,443 at risk EG00111 events8 affected9,451 at risk
Respiratory Tract Oedema	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rhinitis Allergic	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Sleep Apnoea Syndrome	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0014 events4 affected9,451 at risk
Tonsillolith	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Vocal Cord Disorder	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vocal Cord Polyp	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Wheezing	Respiratory, thoracic and mediastinal disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Angioedema	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0008 events7 affected9,443 at risk EG0014 events4 affected9,451 at risk
Decubitus Ulcer	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dermal Cyst	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dermatitis	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dermatitis Allergic	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dermatitis Atopic	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Dermatitis Bullous	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dermatitis Contact	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dermatitis Exfoliative Generalised	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Dermatomyositis	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Diabetic Foot	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG00011 events11 affected9,443 at risk EG0016 events6 affected9,451 at risk
Diabetic Neuropathic Ulcer	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Diabetic Ulcer	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Drug Eruption	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Drug Reaction With Eosinophilia And Systemic Symptoms	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Eczema Nummular	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Erythema	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Erythema Multiforme	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Erythrodermic Psoriasis	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hyperhidrosis	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Intertrigo	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Photosensitivity Reaction	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Pruritus Allergic	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Psoriasis	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events1 affected9,451 at risk
Rash	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Rash Erythematous	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Rash Pruritic	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Scar Pain	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Skin Lesion	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Skin Ulcer	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0013 events3 affected9,451 at risk
Swelling Face	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Urticaria	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0014 events4 affected9,451 at risk
Urticaria Chronic	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Vascular Purpura	Skin and subcutaneous tissue disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Physical Assault	Social circumstances	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Accelerated Hypertension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0013 events3 affected9,451 at risk
Aortic Aneurysm	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00012 events12 affected9,443 at risk EG00110 events10 affected9,451 at risk
Aortic Aneurysm Rupture	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Aortic Dissection	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Aortic Intramural Haematoma	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Aortic Stenosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Aortic Thrombosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Aorto-Duodenal Fistula	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arterial Insufficiency	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arteriosclerosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Arteriovenous Fistula	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Blood Pressure Inadequately Controlled	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Circulatory Collapse	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Deep Vein Thrombosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0009 events8 affected9,443 at risk EG00113 events11 affected9,451 at risk
Dry Gangrene	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0010 events0 affected9,451 at risk
Embolism	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Embolism Venous	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Essential Hypertension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Extremity Necrosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Haematoma	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0013 events3 affected9,451 at risk
Hot Flush	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Hypertension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00041 events36 affected9,443 at risk EG00135 events34 affected9,451 at risk
Hypertensive Crisis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00019 events17 affected9,443 at risk EG00122 events21 affected9,451 at risk
Hypertensive Emergency	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0007 events4 affected9,443 at risk EG0013 events3 affected9,451 at risk
Hypotension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00017 events17 affected9,443 at risk EG00116 events16 affected9,451 at risk
Hypovolaemic Shock	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0011 events1 affected9,451 at risk
Iliac Artery Embolism	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Iliac Artery Occlusion	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Intermittent Claudication	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0007 events6 affected9,443 at risk EG0014 events4 affected9,451 at risk
Ischaemic Limb Pain	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Leriche Syndrome	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Lymphatic Fistula	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lymphoedema	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Lymphorrhoea	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Malignant Hypertension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0004 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Orthostatic Hypotension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Penetrating Aortic Ulcer	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Peripheral Arterial Occlusive Disease	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00049 events47 affected9,443 at risk EG00129 events27 affected9,451 at risk
Peripheral Artery Aneurysm	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0016 events5 affected9,451 at risk
Peripheral Artery Dissection	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Peripheral Artery Occlusion	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00015 events13 affected9,443 at risk EG0017 events7 affected9,451 at risk
Peripheral Artery Stenosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00011 events8 affected9,443 at risk EG0019 events8 affected9,451 at risk
Peripheral Artery Thrombosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0005 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Peripheral Embolism	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Peripheral Ischaemia	Vascular disorders	MedDra 20.1	Systematic Assessment	EG00023 events20 affected9,443 at risk EG0017 events7 affected9,451 at risk
Peripheral Vascular Disorder	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0006 events6 affected9,443 at risk EG0013 events3 affected9,451 at risk
Peripheral Venous Disease	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0012 events2 affected9,451 at risk
Phlebitis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Phlebitis Superficial	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Raynaud's Phenomenon	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Renovascular Hypertension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Shock	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0013 events3 affected9,451 at risk
Shock Haemorrhagic	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0004 events4 affected9,443 at risk EG0011 events1 affected9,451 at risk
Subclavian Artery Occlusion	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Subclavian Artery Stenosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0002 events2 affected9,443 at risk EG0011 events1 affected9,451 at risk
Superior Vena Cava Occlusion	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Temporal Arteritis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Thrombophlebitis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Thrombophlebitis Superficial	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0013 events3 affected9,451 at risk
Thrombosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk
Varicose Vein	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0003 events3 affected9,443 at risk EG0010 events0 affected9,451 at risk
Venous Thrombosis	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0000 events0 affected9,443 at risk EG0011 events1 affected9,451 at risk
Venous Thrombosis Limb	Vascular disorders	MedDra 20.1	Systematic Assessment	EG0001 events1 affected9,443 at risk EG0010 events0 affected9,451 at risk

Other Adverse Events

Term	Organ System	Source Vocabulary	Assessment Type	Statistical Information
Non-Cardiac Chest Pain	General disorders	MedDra 20.1	Systematic Assessment	EG000556 events462 affected9,443 at risk EG001591 events481 affected9,451 at risk
Nasopharyngitis	Infections and infestations	MedDra 20.1	Systematic Assessment	EG000697 events532 affected9,443 at risk EG001713 events567 affected9,451 at risk
Blood Creatine Phosphokinase Increased	Investigations	MedDra 20.1	Systematic Assessment	EG000560 events488 affected9,443 at risk EG001521 events457 affected9,451 at risk
Myalgia	Musculoskeletal and connective tissue disorders	MedDra 20.1	Systematic Assessment	EG000563 events496 affected9,443 at risk EG001591 events522 affected9,451 at risk
Hypertension	Vascular disorders	MedDra 20.1	Systematic Assessment	EG000678 events574 affected9,443 at risk EG001600 events542 affected9,451 at risk

ID	Term
D001161	Arteriosclerosis
D001157	Arterial Occlusive Diseases
D014652	Vascular Diseases
D002318	Cardiovascular Diseases