A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome
Primary Objective:
To compare the effect of alirocumab with placebo on the occurrence of cardiovascular (CV) events (composite endpoint of coronary heart disease (CHD) death, non-fatal myocardial infarction (MI), fatal and non-fatal ischemic stroke, unstable angina (UA) requiring hospitalization) in participants who experienced an acute coronary syndrome (ACS) event 4 to 52 weeks prior to randomization and were treated with evidence-based medical and dietary management of dyslipidemia.
Secondary Objectives:
18924 number of participants aged >= 40 years old were randomized in the study.
Inclusion criteria :
Recently (< 52 weeks) hospitalized for ACS.
Exclusion criteria:
The above information is not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.
Atlantis, Arizona 33462, United States
Newport Beach, Arizona 92663, United States
Mount Clemens, Florida, United States
Framingham, Maine 01702, United States
Marquette, Missouri, United States
Mountain Lakes, North Dakota, United States
Caba, C1093AAS, Argentina
Caba, C1118AAE, Argentina
Caba, C1119ACN, Argentina
Caba, C1180AAX, Argentina
Caba, C1181ACH, Argentina
Caba, C1425AGC, Argentina
Caba, C1426EGR, Argentina
Ciudad de Buenos Aires, C1428DCO, Argentina
Riberao Preto, 14048-900, Brazil
Bogota D.C., Colombia
Espinal - Tolima, Colombia
Praha 5 - Motol, 15006, Czechia
Viljandimaa, 71024, Estonia
Homburg/Saar, 66421, Germany
Rüdersdorf Bei Berlin, 15562, Germany
Haidari, 12462, Greece
N. Ionia, 14233, Greece
Secunderabad, Hyderabad, 500003, India
Vijaywada, 520002, India
Vishkhapattanam, 530013, India
Amagasaki-Shi, Japan
Amagasaki-Shi, Japan
Hachioji-Shi, Japan
Higashihiroshima-Shi, Japan
Higashiibaraki-Gun, Japan
Itabashi-Ku, Japan
Itabashi-Ku, Japan
Kitakyushu-Shi, Japan
Koga-Shi, Japan
Komatsu-Shi, Japan
Komatsushima-Shi, Japan
Kure-Shi, Japan
Kurume-Shi, Japan
Kusatsu-Shi, Japan
Nerima-Ku, Japan
Sagamihara-Shi, Japan
Shinagawa-Ku, Japan
Suita-Shi, Japan
Urasoe-Shi, Japan
W?Grów, 07-100, Poland
Vila Nova Gaia, 4434-502, Portugal
Western Cape, 7500, South Africa
Division of Cardiology, 833, Taiwan
Taoyuan Hsien, Taiwan
Yunlin, Taiwan
Klong Luang, 12120, Thailand
Moung, 30000, Thailand
Muang, 50200, Thailand
Pratumwan, 10400, Thailand
Vinnitsya, 21100, Ukraine
Zaporizhia, 69005, Ukraine
Cumbria, LA14 4LF, United Kingdom