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Zinc supplement is a popular trace element gave to Female pattern hair loss (FPHL) patient. But the type of patient, efficacy, and side effect in detail of zinc supplement are not well characterized. The purpose of this study is to determine efficacy and side effect of chelated zinc in FPHL who using 5%minoxidil solution.
5%minoxidil solution is standard treatment for Female pattern hair loss (FPHL) patient. We gave 15mg chelate Zinc / Placebo drug to patient as an additional trace element. Then measure growth of hair by Global photograph, Microscope hair count, micrometer and record case and side effect during 10 months of treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chelate zinc suppliment | Experimental | 15mg Chelate zinc suppliment : additional to standard 5% minoxidil |
|
| Placebo drug | Placebo Comparator | Placebo drug to compare with 15mg chelated Zn : additional to standard 5% minoxidil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 15 mg Chelate zinc supplement | Drug | 15 mg Chelate zinc additional to standard 5% minoxidil |
|
| Measure | Description | Time Frame |
|---|---|---|
| Compare clinical improvement before and after treatment | Measure clinical by Global photographic view using 7 point scale. Review picture by 2 dermatologist | 6 month |
| Compare hair density before and after treatmen | Measure Hair density by microscope photo of area 1 cm2. Conut number of hair in photo. | 6 month |
| Compare average hair shaft diameter before and after treatment | Compare average hair shaft diameter before and after treatment Measure hair shaft diameter using electronic outside micrometer. | 6 month |
| Measure | Description | Time Frame |
|---|---|---|
| Number of pateint with Side effect | Using side effect record form to record side effect from treatment Count number of pateint with side effect. | 6 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rattapon Thuangtong, MD | Contact | +662 419-7000 | 4333 | rattapongthuangtong@yahoo.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Siriraj Hospital | Recruiting | Bangkok | 10700 | Thailand |
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| ID | Term |
|---|---|
| D000505 | Alopecia |
| ID | Term |
|---|---|
| D007039 | Hypotrichosis |
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D015032 | Zinc |
| D013213 | Starch |
| ID | Term |
|---|---|
| D019216 | Metals, Heavy |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D028561 | Transition Elements |
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| Placebo drug supplement | Drug | Placebo drug instead of Zinc supplement |
|
|
| D020763 |
| Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D008670 |
| Metals |
| D005936 | Glucans |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D011134 | Polysaccharides |