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Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation that delivers ventilatory assist in proportion to neural effort. It was a controlled randomized single-center prospective study in order to explore the efficacy of this new mode of mechanical ventilation after corrective open-heart surgery for congenital heart disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NAVA group | Experimental | Patients ventilated with the mode of neurally adjusted ventilatory assist |
|
| PSV group | Active Comparator | Patients ventilated with the mode of pressure support ventilation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mode of neurally adjusted ventilatory assist | Device | patients ventilated with the mode of neurally adjusted ventilatory assist after corrective open-heart surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| Asynchrony index and Comfort Scale | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Dosage of sedatives | 2 weeks | |
| hemodynamics | 2 weeks | |
| Duration of mechanical ventilation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Limin Zhu, MD | Contact | 8621-38626161 | 6622 | zhulimin121@hotmail.com |
| Zhuoming Xu, MD PhD | Contact | 8621-38626161 | 6623 | zmxyfb@yahoo.com.cn |
| Name | Affiliation | Role |
|---|---|---|
| Limin Zhu, MD | Cardiac intensive care unit, Department of Thoracic and cardiovascular Surgery, Shanghai children's Medical Center | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cardiac intensive care unit, Department of cardiothoracic vascular surgery, Shanghai Children's Medical Center, Medical college of Shanghai Jiaotong University | Recruiting | Shanghai | 200127 | China |
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| Mode of pressure support ventilation | Device | Patients ventilated with the mode of pressure support ventilation after corrective open-heart surgery |
|
| 2 weeks |
| Gas exchange | 2 weeks |
| Length of ICU stay | 2 weeks |
|
| ID | Term |
|---|---|
| D006330 | Heart Defects, Congenital |
| ID | Term |
|---|---|
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
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