Fully Covered or Partially Covered Stents in Malignant Esophageal Strictures

A Randomized Comparison of a Fully Covered Self Expandable Metal Stent Versus a Partially Covered Self Expandable Metal Stent in Malignant Esophageal Strictures

The purpose of this study is to determine whether fully covered or partially covered metal stents are more favorable in incurable malignant stenosis of the esophagus or cardia. Primary outcome will be the occurence of recurrent dysphagia which is defined as dysphagia due to a stent or tumour related cause in a 6-month follow-up

Inclusion Criteria:

• Malignant stricture of the esophagus or cardia
• No curative treatment options available
• Dysphagia grade of at least 2 (i.e. swallow semi-solid foods or less)
• Informed consent
• Age ≥ 18 years

Exclusion Criteria:

• Previous treatment with self-expandable metal stent for same condition
• Evidence of tumor within 2 cm of the upper esophageal sphincter.
• Presence of an esophago-tracheal or -bronchial fistula or both.
• Not able to undergo upper endoscopy