Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients

Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients: a Prospective Multivariate Analysis of Prognostic Factors and Haemostaseological Findings

In a prospective observational study the incidence of Heparin-induced Thrombocytopenia (HIT) Type 2 after orthotopic liver transplantation, associated factors, and hemostaseological findings in thrombocytes and anti-body patterns is going to be investigated.

The investigators examined the frequency of anti-PF4/heparin antibodies (IgG/M/A; EIA) and their functional activity (HIPA) in 38 whole organ deceased donor liver transplant recipients. Additionally, demographic, clinical, donor- and recipient-specific parameters and laboratory findings (ALAT, ASAT, cholinesterase) were investigated.

Inclusion Criteria:

• all consecutive liver transplant recipients between 01/2010 and 08/2011 who
• were transplanted at our center after allocation of a liver graft via Eurotransplant

Exclusion Criteria:

• patient's refusal to participate in prospective observation