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The objectives of this study are to investigate how oral 5-ASA drugs have been used in the condition without symptoms such as abdominal pain or diarrhea/bloody stool (remission stage), or in the transition from the condition with symptoms such as abdominal pain or diarrhea/bloody stool (active stage) to the remission stage in ulcerative colitis and to study how many patients will be able to maintain the remission stage during the observation period and how many times the patients will experience the active stage (relapse), as well as how symptoms will change during the observation period to discover better treatment plans.
Period: 2012-2014 Observation Time: 0, 26week, 52week
Matters investigated:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 5-ASA | Patient's treated with oral 5-ASA |
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| Measure | Description | Time Frame |
|---|---|---|
| Cumulative non-relapse rate | 52 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Number of relapses | 52 weeks | |
| The pUCDAI scores and the scores that constitute these pUCDAI scores at each assessment period | 0, 26 weeks, 52 weeks | |
| Medication adherence:Measured by patient response to visual analog scale |
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Inclusion Criteria:
Exclusion Criteria:
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University, Main hospital, General Hospital, General Practitioner
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| Name | Affiliation | Role |
|---|---|---|
| Soji Omuro, Mr. | Kyorin Pharmaceutical Co.,Ltd | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tokyo Medical and Dental University | Bunkyo-ku | Tokyo | 113-8519 | Japan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28390410 | Derived | Nagahori M, Kochi S, Hanai H, Yamamoto T, Nakamura S, Omuro S, Watanabe M, Hibi T; OPTIMUM Study Group. Real life results in using 5-ASA for maintaining mild to moderate UC patients in Japan, a multi-center study, OPTIMUM Study. BMC Gastroenterol. 2017 Apr 4;17(1):47. doi: 10.1186/s12876-017-0604-y. |
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| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| 0, 26 weeks, 52 weeks |
| D015212 |
| Inflammatory Bowel Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D001519 | Behavior |